1nya
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(New page: 200px<br /><applet load="1nya" size="450" color="white" frame="true" align="right" spinBox="true" caption="1nya" /> '''NMR SOLUTION STRUCTURE OF CALERYTHRIN, AN EF...) |
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'''NMR SOLUTION STRUCTURE OF CALERYTHRIN, AN EF-HAND CALCIUM-BINDING PROTEIN'''<br /> | '''NMR SOLUTION STRUCTURE OF CALERYTHRIN, AN EF-HAND CALCIUM-BINDING PROTEIN'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The structure of calerythrin, a prokaryotic 20 kDa calcium-binding protein | + | The structure of calerythrin, a prokaryotic 20 kDa calcium-binding protein has been determined by solution NMR spectroscopy. Distance, dihedral angle, J coupling, secondary chemical shift, residual dipolar coupling and radius of gyration restraints reveal four EF-hand motifs arranged in a compact globular structure. A tight turn in the middle of the amino acid sequence brings the two halves, each comprising a pair of EF-hands, close together. The structural similarity between calerythrin and the eukaryotic sarcoplasmic calcium-binding proteins is notable. |
==About this Structure== | ==About this Structure== | ||
| - | 1NYA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharopolyspora_erythraea Saccharopolyspora erythraea] with CA as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http:// | + | 1NYA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharopolyspora_erythraea Saccharopolyspora erythraea] with <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NYA OCA]. |
==Reference== | ==Reference== | ||
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[[Category: ef-hand]] | [[Category: ef-hand]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:11:20 2008'' |
Revision as of 12:11, 21 February 2008
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NMR SOLUTION STRUCTURE OF CALERYTHRIN, AN EF-HAND CALCIUM-BINDING PROTEIN
Overview
The structure of calerythrin, a prokaryotic 20 kDa calcium-binding protein has been determined by solution NMR spectroscopy. Distance, dihedral angle, J coupling, secondary chemical shift, residual dipolar coupling and radius of gyration restraints reveal four EF-hand motifs arranged in a compact globular structure. A tight turn in the middle of the amino acid sequence brings the two halves, each comprising a pair of EF-hands, close together. The structural similarity between calerythrin and the eukaryotic sarcoplasmic calcium-binding proteins is notable.
About this Structure
1NYA is a Single protein structure of sequence from Saccharopolyspora erythraea with as ligand. Full crystallographic information is available from OCA.
Reference
NMR solution structure of calerythrin, an EF-hand calcium-binding protein from Saccharopolyspora erythraea., Tossavainen H, Permi P, Annila A, Kilpelainen I, Drakenberg T, Eur J Biochem. 2003 Jun;270(11):2505-12. PMID:12755706
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