3n84

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{{STRUCTURE_3n84| PDB=3n84 | SCENE= }}
{{STRUCTURE_3n84| PDB=3n84 | SCENE= }}
===Crystal Structure of the Grb2 SH2 Domain in Complex with a 23-Membered Macrocyclic Ligand Having the Sequence pYVNVP===
===Crystal Structure of the Grb2 SH2 Domain in Complex with a 23-Membered Macrocyclic Ligand Having the Sequence pYVNVP===
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{{ABSTRACT_PUBMED_21116482}}
{{ABSTRACT_PUBMED_21116482}}
==About this Structure==
==About this Structure==
[[3n84]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N84 OCA].
[[3n84]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N84 OCA].
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==See Also==
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*[[Growth factor receptor-bound protein 2|Growth factor receptor-bound protein 2]]
==Reference==
==Reference==
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<ref group="xtra">PMID:21116482</ref><references group="xtra"/>
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<ref group="xtra">PMID:021116482</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Clements, J H.]]
[[Category: Clements, J H.]]
[[Category: Martin, S F.]]
[[Category: Martin, S F.]]
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[[Category: Golgi apparatus]]
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[[Category: Host-virus interaction]]
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[[Category: Ligand preorganization]]
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[[Category: Macrocycle]]
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[[Category: Macrocyclic ligand]]
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[[Category: Phosphoprotein]]
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[[Category: Protein binding-peptide complex]]

Revision as of 21:47, 20 October 2012

Template:STRUCTURE 3n84

Contents

Crystal Structure of the Grb2 SH2 Domain in Complex with a 23-Membered Macrocyclic Ligand Having the Sequence pYVNVP

Template:ABSTRACT PUBMED 21116482

About this Structure

3n84 is a 12 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Delorbe JE, Clements JH, Whiddon BB, Martin SF. Thermodynamic and Structural Effects of Macrocyclization as a Constraining Method in Protein-Ligand Interactions. ACS Med Chem Lett. 2010 Nov 11;1(8):448-452. PMID:21116482 doi:10.1021/ml100142y

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