3l95
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
| - | [[3l95]] is a 6 chain structure | + | [[3l95]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L95 OCA]. |
==See Also== | ==See Also== | ||
Revision as of 22:10, 20 October 2012
Contents |
Crystal structure of the human Notch1 Negative Regulatory Region (NRR) bound to the fab fragment of an antagonist antibody
Template:ABSTRACT PUBMED 20393564
About this Structure
3l95 is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Wu Y, Cain-Hom C, Choy L, Hagenbeek TJ, de Leon GP, Chen Y, Finkle D, Venook R, Wu X, Ridgway J, Schahin-Reed D, Dow GJ, Shelton A, Stawicki S, Watts RJ, Zhang J, Choy R, Howard P, Kadyk L, Yan M, Zha J, Callahan CA, Hymowitz SG, Siebel CW. Therapeutic antibody targeting of individual Notch receptors. Nature. 2010 Apr 15;464(7291):1052-7. PMID:20393564 doi:10.1038/nature08878
Categories: Homo sapiens | Hymowitz, S G. | Leon, G P.de. | Activator | Alpha-beta-sandwich | Ank repeat | Antibody | Cell cycle | Cell membrane | Developmental protein | Differentiation | Egf-like domain | Fab fragment | Glycoprotein | Hd domain | Immune system | Lin12 notch cysteine-rich | Lnr | Membrane | Metal-binding | Notch signaling pathway | Nrr | Sea domain | Signaling protein
