1oia
From Proteopedia
(New page: 200px<br /> <applet load="1oia" size="450" color="white" frame="true" align="right" spinBox="true" caption="1oia, resolution 2.40Å" /> '''U1A RNP DOMAIN 1-95...) |
|||
| Line 1: | Line 1: | ||
| - | [[Image:1oia.gif|left|200px]]<br /> | + | [[Image:1oia.gif|left|200px]]<br /><applet load="1oia" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="1oia" size=" | + | |
caption="1oia, resolution 2.40Å" /> | caption="1oia, resolution 2.40Å" /> | ||
'''U1A RNP DOMAIN 1-95'''<br /> | '''U1A RNP DOMAIN 1-95'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The crystal structure of the RNA binding domain of the U1 small nuclear | + | The crystal structure of the RNA binding domain of the U1 small nuclear ribonucleoprotein A, which forms part of the ribonucleoprotein complex involved in the excision of introns, has been solved. It contains a four-stranded beta sheet and two alpha helices. The highly conserved segments designated RNP1 and RNP2 lie side by side on the middle two beta strands. U1 RNA binding studies of mutant proteins suggest that the RNA binds to the four-stranded beta sheet and to the flexible loops on one end. |
==About this Structure== | ==About this Structure== | ||
| - | 1OIA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure | + | 1OIA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 1NRC. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OIA OCA]. |
==Reference== | ==Reference== | ||
| Line 14: | Line 13: | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Evans, P | + | [[Category: Evans, P R.]] |
[[Category: Nagai, K.]] | [[Category: Nagai, K.]] | ||
[[Category: nuclear protein]] | [[Category: nuclear protein]] | ||
| Line 20: | Line 19: | ||
[[Category: rna-binding]] | [[Category: rna-binding]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:18:06 2008'' |
Revision as of 12:18, 21 February 2008
|
U1A RNP DOMAIN 1-95
Overview
The crystal structure of the RNA binding domain of the U1 small nuclear ribonucleoprotein A, which forms part of the ribonucleoprotein complex involved in the excision of introns, has been solved. It contains a four-stranded beta sheet and two alpha helices. The highly conserved segments designated RNP1 and RNP2 lie side by side on the middle two beta strands. U1 RNA binding studies of mutant proteins suggest that the RNA binds to the four-stranded beta sheet and to the flexible loops on one end.
About this Structure
1OIA is a Single protein structure of sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1NRC. Full crystallographic information is available from OCA.
Reference
Crystal structure of the RNA-binding domain of the U1 small nuclear ribonucleoprotein A., Nagai K, Oubridge C, Jessen TH, Li J, Evans PR, Nature. 1990 Dec 6;348(6301):515-20. PMID:2147232
Page seeded by OCA on Thu Feb 21 14:18:06 2008
