1as4
From Proteopedia
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[[Image:1as4.png|left|200px]] | [[Image:1as4.png|left|200px]] | ||
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{{STRUCTURE_1as4| PDB=1as4 | SCENE= }} | {{STRUCTURE_1as4| PDB=1as4 | SCENE= }} | ||
===CLEAVED ANTICHYMOTRYPSIN A349R=== | ===CLEAVED ANTICHYMOTRYPSIN A349R=== | ||
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{{ABSTRACT_PUBMED_9521649}} | {{ABSTRACT_PUBMED_9521649}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Alpha-1-antichymotrypsin deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=107280 107280]], Cerebrovascular disease, occlusive OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=107280 107280]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1as4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AS4 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:009521649</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Christianson, D W.]] | [[Category: Christianson, D W.]] | ||
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[[Category: Serine protease inhibitor]] | [[Category: Serine protease inhibitor]] | ||
[[Category: Serpin]] | [[Category: Serpin]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:25:08 2009'' | ||
Revision as of 11:53, 21 October 2012
CLEAVED ANTICHYMOTRYPSIN A349R
Template:ABSTRACT PUBMED 9521649
About this Structure
1as4 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Lukacs CM, Rubin H, Christianson DW. Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction. Biochemistry. 1998 Mar 10;37(10):3297-304. PMID:9521649 doi:10.1021/bi972359e
