1cjb
From Proteopedia
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{{STRUCTURE_1cjb| PDB=1cjb | SCENE= }} | {{STRUCTURE_1cjb| PDB=1cjb | SCENE= }} | ||
===MALARIAL PURINE PHOSPHORIBOSYLTRANSFERASE=== | ===MALARIAL PURINE PHOSPHORIBOSYLTRANSFERASE=== | ||
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{{ABSTRACT_PUBMED_10433693}} | {{ABSTRACT_PUBMED_10433693}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1cjb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CJB OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:010433693</ref><ref group="xtra">PMID:016516468</ref><references group="xtra"/> |
[[Category: Hypoxanthine phosphoribosyltransferase]] | [[Category: Hypoxanthine phosphoribosyltransferase]] | ||
[[Category: Plasmodium falciparum]] | [[Category: Plasmodium falciparum]] | ||
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[[Category: Phosphoribosyltransferase]] | [[Category: Phosphoribosyltransferase]] | ||
[[Category: Purine salvage]] | [[Category: Purine salvage]] | ||
| + | [[Category: Transferase]] | ||
[[Category: Transition state inhibitor]] | [[Category: Transition state inhibitor]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:22:19 2009'' | ||
Revision as of 20:07, 21 October 2012
MALARIAL PURINE PHOSPHORIBOSYLTRANSFERASE
Template:ABSTRACT PUBMED 10433693
About this Structure
1cjb is a 4 chain structure with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.
Reference
- Shi W, Li CM, Tyler PC, Furneaux RH, Cahill SM, Girvin ME, Grubmeyer C, Schramm VL, Almo SC. The 2.0 A structure of malarial purine phosphoribosyltransferase in complex with a transition-state analogue inhibitor. Biochemistry. 1999 Aug 3;38(31):9872-80. PMID:10433693 doi:10.1021/bi990664p
- Joshi AA, Viswanathan CL. Docking studies and development of novel 5-heteroarylamino-2,4-diamino-8-chloropyrimido-[4,5-b]quinolines as potential antimalarials. Bioorg Med Chem Lett. 2006 May 15;16(10):2613-7. Epub 2006 Mar 3. PMID:16516468 doi:10.1016/j.bmcl.2006.02.038
