1c3e
From Proteopedia
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===NEW INSIGHTS INTO INHIBITOR DESIGN FROM THE CRYSTAL STRUCTURE AND NMR STUDIES OF E. COLI GAR TRANSFORMYLATE IN COMPLEX WITH BETA-GAR AND 10-FORMYL-5,8,10-TRIDEAZAFOLIC ACID.=== | ===NEW INSIGHTS INTO INHIBITOR DESIGN FROM THE CRYSTAL STRUCTURE AND NMR STUDIES OF E. COLI GAR TRANSFORMYLATE IN COMPLEX WITH BETA-GAR AND 10-FORMYL-5,8,10-TRIDEAZAFOLIC ACID.=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1c3e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C3E OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:010606510</ref><references group="xtra"/> |
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Phosphoribosylglycinamide formyltransferase]] | [[Category: Phosphoribosylglycinamide formyltransferase]] | ||
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[[Category: Inhibitor complex]] | [[Category: Inhibitor complex]] | ||
[[Category: Purine biosynthesis]] | [[Category: Purine biosynthesis]] | ||
| - | + | [[Category: Transferase]] | |
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Revision as of 20:23, 21 October 2012
NEW INSIGHTS INTO INHIBITOR DESIGN FROM THE CRYSTAL STRUCTURE AND NMR STUDIES OF E. COLI GAR TRANSFORMYLATE IN COMPLEX WITH BETA-GAR AND 10-FORMYL-5,8,10-TRIDEAZAFOLIC ACID.
Template:ABSTRACT PUBMED 10606510
About this Structure
1c3e is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
- Greasley SE, Yamashita MM, Cai H, Benkovic SJ, Boger DL, Wilson IA. New insights into inhibitor design from the crystal structure and NMR studies of Escherichia coli GAR transformylase in complex with beta-GAR and 10-formyl-5,8,10-trideazafolic acid. Biochemistry. 1999 Dec 21;38(51):16783-93. PMID:10606510
