This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1oxk
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="1oxk" size="450" color="white" frame="true" align="right" spinBox="true" caption="1oxk, resolution 2.10Å" /> '''Complex between YPD1...) |
|||
| Line 1: | Line 1: | ||
| - | [[Image:1oxk.gif|left|200px]]<br /><applet load="1oxk" size=" | + | [[Image:1oxk.gif|left|200px]]<br /><applet load="1oxk" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1oxk, resolution 2.10Å" /> | caption="1oxk, resolution 2.10Å" /> | ||
'''Complex between YPD1 and SLN1 response regulator domain in space group P3(2)'''<br /> | '''Complex between YPD1 and SLN1 response regulator domain in space group P3(2)'''<br /> | ||
| - | |||
| - | ==Overview== | ||
| - | In Saccharomyces cerevisiae, a branched multistep phosphorelay signaling, pathway regulates cellular adaptation to hyperosmotic stress. YPD1, functions as a histidine-phosphorylated protein intermediate required for, phosphoryl group transfer from a membrane-bound sensor histidine kinase, (SLN1) to two distinct response regulator proteins (SSK1 and SKN7). These, four proteins are evolutionarily related to the well-characterized, "two-component" regulatory proteins from bacteria. Although structural, information is available for many two-component signaling proteins, there, are very few examples of complexes between interacting phosphorelay, partners. Here we report the first crystal structure of a prototypical, monomeric histidine-containing phosphotransfer (HPt) protein YPD1 in, complex with its upstream phosphodonor, the response regulator domain, associated with SLN1. | ||
==About this Structure== | ==About this Structure== | ||
| - | 1OXK is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with SO4 as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http:// | + | 1OXK is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OXK OCA]. |
| - | + | ||
| - | + | ||
| - | + | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| - | [[Category: Porter, S | + | [[Category: Porter, S W.]] |
| - | [[Category: West, A | + | [[Category: West, A H.]] |
[[Category: Xu, Q.]] | [[Category: Xu, Q.]] | ||
[[Category: SO4]] | [[Category: SO4]] | ||
| Line 25: | Line 19: | ||
[[Category: ypd1p]] | [[Category: ypd1p]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:25:45 2008'' |
Revision as of 12:25, 21 February 2008
|
Complex between YPD1 and SLN1 response regulator domain in space group P3(2)
About this Structure
1OXK is a Protein complex structure of sequences from Saccharomyces cerevisiae with as ligand. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Feb 21 14:25:45 2008
