1oxk
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="1oxk" size="450" color="white" frame="true" align="right" spinBox="true" caption="1oxk, resolution 2.10Å" /> '''Complex between YPD1...) |
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| - | [[Image:1oxk.gif|left|200px]]<br /><applet load="1oxk" size=" | + | [[Image:1oxk.gif|left|200px]]<br /><applet load="1oxk" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1oxk, resolution 2.10Å" /> | caption="1oxk, resolution 2.10Å" /> | ||
'''Complex between YPD1 and SLN1 response regulator domain in space group P3(2)'''<br /> | '''Complex between YPD1 and SLN1 response regulator domain in space group P3(2)'''<br /> | ||
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| - | ==Overview== | ||
| - | In Saccharomyces cerevisiae, a branched multistep phosphorelay signaling, pathway regulates cellular adaptation to hyperosmotic stress. YPD1, functions as a histidine-phosphorylated protein intermediate required for, phosphoryl group transfer from a membrane-bound sensor histidine kinase, (SLN1) to two distinct response regulator proteins (SSK1 and SKN7). These, four proteins are evolutionarily related to the well-characterized, "two-component" regulatory proteins from bacteria. Although structural, information is available for many two-component signaling proteins, there, are very few examples of complexes between interacting phosphorelay, partners. Here we report the first crystal structure of a prototypical, monomeric histidine-containing phosphotransfer (HPt) protein YPD1 in, complex with its upstream phosphodonor, the response regulator domain, associated with SLN1. | ||
==About this Structure== | ==About this Structure== | ||
| - | 1OXK is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with SO4 as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http:// | + | 1OXK is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OXK OCA]. |
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[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| - | [[Category: Porter, S | + | [[Category: Porter, S W.]] |
| - | [[Category: West, A | + | [[Category: West, A H.]] |
[[Category: Xu, Q.]] | [[Category: Xu, Q.]] | ||
[[Category: SO4]] | [[Category: SO4]] | ||
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[[Category: ypd1p]] | [[Category: ypd1p]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:25:45 2008'' |
Revision as of 12:25, 21 February 2008
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Complex between YPD1 and SLN1 response regulator domain in space group P3(2)
About this Structure
1OXK is a Protein complex structure of sequences from Saccharomyces cerevisiae with as ligand. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Feb 21 14:25:45 2008
