Bungarotoxin

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[[Image:2abx.png|left|200px|thumb|Crystal Structure of α-Bungarotoxin [[2abx]]]]
[[Image:2abx.png|left|200px|thumb|Crystal Structure of α-Bungarotoxin [[2abx]]]]
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{{STRUCTURE_2abx| PDB=2abx | SIZE=400| SCENE=Bungarotoxin/Cv/1 |right|CAPTION=α-Bungarotoxin [[2abx]] }}
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{{STRUCTURE_2abx| PDB=2abx | SIZE=400| SCENE=Bungarotoxin/Cv/1 |right|CAPTION=α-Bungarotoxin dimer [[2abx]] }}
[[Bungarotoxin|Bungarotoxins]]. α-Bungarotoxin (α-BGT), β-Bungarotoxin (β-BGT), γ-Bungarotoxin (γ-BGT) and κ-Bungarotoxin (κ-BGT) are snake toxins from banded krait. α-BGT binds irreversibly to the acetylcholine receptor (AChR) causing paralysis and death. See details in [[Alpha-bungarotoxin]]. β-BGT binds to the presynaptic terminal causing release of acetylcholine. The images at the left and at the right correspond to one representative Bungarotoxin , ''i.e.'' the crystal structure of α-Bungarotoxin ([[2abx]]). For toxins in Proteopedia see [[Toxins]].
[[Bungarotoxin|Bungarotoxins]]. α-Bungarotoxin (α-BGT), β-Bungarotoxin (β-BGT), γ-Bungarotoxin (γ-BGT) and κ-Bungarotoxin (κ-BGT) are snake toxins from banded krait. α-BGT binds irreversibly to the acetylcholine receptor (AChR) causing paralysis and death. See details in [[Alpha-bungarotoxin]]. β-BGT binds to the presynaptic terminal causing release of acetylcholine. The images at the left and at the right correspond to one representative Bungarotoxin , ''i.e.'' the crystal structure of α-Bungarotoxin ([[2abx]]). For toxins in Proteopedia see [[Toxins]].

Revision as of 10:26, 25 October 2012

Image:2abx.png
Crystal Structure of α-Bungarotoxin 2abx

Template:STRUCTURE 2abx

Bungarotoxins. α-Bungarotoxin (α-BGT), β-Bungarotoxin (β-BGT), γ-Bungarotoxin (γ-BGT) and κ-Bungarotoxin (κ-BGT) are snake toxins from banded krait. α-BGT binds irreversibly to the acetylcholine receptor (AChR) causing paralysis and death. See details in Alpha-bungarotoxin. β-BGT binds to the presynaptic terminal causing release of acetylcholine. The images at the left and at the right correspond to one representative Bungarotoxin , i.e. the crystal structure of α-Bungarotoxin (2abx). For toxins in Proteopedia see Toxins.


Contents

3D Structures of Bungarotoxin

Bungarotoxin

2abx – α-BGT
1kfh, 1ik8, 1ikc, 1idi, 1idl, 2nbt – α-BGT - NMR
1bun - β2-BGT
1mr6 – γ-BGT – NMR
1kba – κ-BGT


BGT+binding peptide

1l4w, 1ljz, 1kc4, 1kl8, 1jbd, 1haa, 1haj, 1idg, 1idh, 1hoy, 1bxp, 1abt, 1rgj, 2btx – α-BGT+AChR peptide - NMR
1hc9 - α-BGT+AChR peptide

BGT+ AChR subunit

2qc1 – α-BGT+mAChR a subunit

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Jaime Prilusky

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