Bungarotoxin
From Proteopedia
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[[Image:2abx.png|left|200px|thumb|Crystal Structure of α-Bungarotoxin [[2abx]]]] | [[Image:2abx.png|left|200px|thumb|Crystal Structure of α-Bungarotoxin [[2abx]]]] | ||
- | {{STRUCTURE_2abx| PDB=2abx | SIZE=400| SCENE=Bungarotoxin/Cv/1 |right|CAPTION=α-Bungarotoxin [[2abx]] }} | + | {{STRUCTURE_2abx| PDB=2abx | SIZE=400| SCENE=Bungarotoxin/Cv/1 |right|CAPTION=α-Bungarotoxin dimer [[2abx]] }} |
[[Bungarotoxin|Bungarotoxins]]. α-Bungarotoxin (α-BGT), β-Bungarotoxin (β-BGT), γ-Bungarotoxin (γ-BGT) and κ-Bungarotoxin (κ-BGT) are snake toxins from banded krait. α-BGT binds irreversibly to the acetylcholine receptor (AChR) causing paralysis and death. See details in [[Alpha-bungarotoxin]]. β-BGT binds to the presynaptic terminal causing release of acetylcholine. The images at the left and at the right correspond to one representative Bungarotoxin , ''i.e.'' the crystal structure of α-Bungarotoxin ([[2abx]]). For toxins in Proteopedia see [[Toxins]]. | [[Bungarotoxin|Bungarotoxins]]. α-Bungarotoxin (α-BGT), β-Bungarotoxin (β-BGT), γ-Bungarotoxin (γ-BGT) and κ-Bungarotoxin (κ-BGT) are snake toxins from banded krait. α-BGT binds irreversibly to the acetylcholine receptor (AChR) causing paralysis and death. See details in [[Alpha-bungarotoxin]]. β-BGT binds to the presynaptic terminal causing release of acetylcholine. The images at the left and at the right correspond to one representative Bungarotoxin , ''i.e.'' the crystal structure of α-Bungarotoxin ([[2abx]]). For toxins in Proteopedia see [[Toxins]]. |
Revision as of 10:26, 25 October 2012
Bungarotoxins. α-Bungarotoxin (α-BGT), β-Bungarotoxin (β-BGT), γ-Bungarotoxin (γ-BGT) and κ-Bungarotoxin (κ-BGT) are snake toxins from banded krait. α-BGT binds irreversibly to the acetylcholine receptor (AChR) causing paralysis and death. See details in Alpha-bungarotoxin. β-BGT binds to the presynaptic terminal causing release of acetylcholine. The images at the left and at the right correspond to one representative Bungarotoxin , i.e. the crystal structure of α-Bungarotoxin (2abx). For toxins in Proteopedia see Toxins.
Contents |
3D Structures of Bungarotoxin
Bungarotoxin
2abx – α-BGT
1kfh, 1ik8, 1ikc, 1idi, 1idl, 2nbt – α-BGT - NMR
1bun - β2-BGT
1mr6 – γ-BGT – NMR
1kba – κ-BGT
BGT+binding peptide
1l4w, 1ljz, 1kc4, 1kl8, 1jbd, 1haa, 1haj, 1idg, 1idh, 1hoy, 1bxp, 1abt, 1rgj, 2btx – α-BGT+AChR peptide - NMR
1hc9 - α-BGT+AChR peptide
BGT+ AChR subunit
2qc1 – α-BGT+mAChR a subunit