Ecotin
From Proteopedia
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- | {{STRUCTURE_1id5| PDB=1id5 | SIZE=400| SCENE= |right|CAPTION=A monomer of the dimeric E. coli ecotin (gold) complex with thrombin heavy chain (pink) and light chain (aqua) | + | {{STRUCTURE_1id5| PDB=1id5 | SIZE=400| SCENE= |right|CAPTION=A monomer of the dimeric E. coli ecotin (gold) complex with thrombin heavy chain (pink) and light chain (aqua), protease inhibitor and Ca+2 ion [[1id5]] }} |
'''Ecotin''' (ECO) is a serine protease inhibitor found in the periplasm of E. coli. It is a potent anti and a reversible tight-binding inhibitor of human factor Xa. | '''Ecotin''' (ECO) is a serine protease inhibitor found in the periplasm of E. coli. It is a potent anti and a reversible tight-binding inhibitor of human factor Xa. |
Revision as of 08:13, 30 October 2012
Ecotin (ECO) is a serine protease inhibitor found in the periplasm of E. coli. It is a potent anti and a reversible tight-binding inhibitor of human factor Xa.
Contents |
3D Structures of Ecotin
Updated November 2011
1ecy, 1ecz – ECO - Escherichia coli
1ifg - ECO (mutant)
Ecotin complex with protein
1slu, 1slv, 1slw, 1slx, 1ezs, 1ezu – ECO (mutant) + anionic trypsin (mutant)
1azz – ECO + collagenase
1id5 - ECO (mutant) + thrombin
1n8o, 1y6t, 2y6t - ECO + chymotrypsin
1p0s - ECO (mutant) + factor Xa
1xx9 - ECO (mutant) + factor Xi
1xxd, 1xxf - ECO (mutant) + factor Xi (mutant)
1fi8 - ECO (mutant) + granzyme B