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1pkm
From Proteopedia
(New page: 200px<br /><applet load="1pkm" size="450" color="white" frame="true" align="right" spinBox="true" caption="1pkm, resolution 2.6Å" /> '''THE REFINED THREE-DIM...) |
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| - | [[Image:1pkm.jpg|left|200px]]<br /><applet load="1pkm" size=" | + | [[Image:1pkm.jpg|left|200px]]<br /><applet load="1pkm" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1pkm, resolution 2.6Å" /> | caption="1pkm, resolution 2.6Å" /> | ||
'''THE REFINED THREE-DIMENSIONAL STRUCTURE OF CAT MUSCLE (M1) PYRUVATE KINASE, AT A RESOLUTION OF 2.6 ANGSTROMS'''<br /> | '''THE REFINED THREE-DIMENSIONAL STRUCTURE OF CAT MUSCLE (M1) PYRUVATE KINASE, AT A RESOLUTION OF 2.6 ANGSTROMS'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The three-dimensional structure of cat-muscle pyoruvate kinase has been | + | The three-dimensional structure of cat-muscle pyoruvate kinase has been refined at a resolution of 2.6 A. The details of the structure permit interpretation of the original heavy-atom studies and give insight into the importance of conserved residues in pyruvate kinases and the allosteric behaviour of the enzyme. There are a small number of essential residues which determine the relative orientations of domains and the precise nature of intersubunit contacts. Arginine residues are particularly important. |
==About this Structure== | ==About this Structure== | ||
| - | 1PKM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Felis_catus Felis catus]. Active as [http://en.wikipedia.org/wiki/Pyruvate_kinase Pyruvate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.40 2.7.1.40] Full crystallographic information is available from [http:// | + | 1PKM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Felis_catus Felis catus]. Active as [http://en.wikipedia.org/wiki/Pyruvate_kinase Pyruvate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.40 2.7.1.40] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PKM OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Pyruvate kinase]] | [[Category: Pyruvate kinase]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Allen, S | + | [[Category: Allen, S C.]] |
[[Category: Muirhead, H.]] | [[Category: Muirhead, H.]] | ||
[[Category: pyruvate kinase]] | [[Category: pyruvate kinase]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:29:47 2008'' |
Revision as of 12:29, 21 February 2008
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THE REFINED THREE-DIMENSIONAL STRUCTURE OF CAT MUSCLE (M1) PYRUVATE KINASE, AT A RESOLUTION OF 2.6 ANGSTROMS
Overview
The three-dimensional structure of cat-muscle pyoruvate kinase has been refined at a resolution of 2.6 A. The details of the structure permit interpretation of the original heavy-atom studies and give insight into the importance of conserved residues in pyruvate kinases and the allosteric behaviour of the enzyme. There are a small number of essential residues which determine the relative orientations of domains and the precise nature of intersubunit contacts. Arginine residues are particularly important.
About this Structure
1PKM is a Single protein structure of sequence from Felis catus. Active as Pyruvate kinase, with EC number 2.7.1.40 Full crystallographic information is available from OCA.
Reference
Refined three-dimensional structure of cat-muscle (M1) pyruvate kinase at a resolution of 2.6 A., Allen SC, Muirhead H, Acta Crystallogr D Biol Crystallogr. 1996 May 1;52(Pt 3):499-504. PMID:15299671
Page seeded by OCA on Thu Feb 21 14:29:47 2008
