RA Mediated T-reg Differentiation
From Proteopedia
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==Introduction== | ==Introduction== | ||
| - | + | T-regulatory cells (T-regs) are a small subset of CD4+ T-cells that exhibit strong down regulation of immune system activity in their local environment. They are distinguished from other CD4+ T-cells by the expression of FOXP3, a gene regulator. | |
<StructureSection load='1dq8' size='350' side='left' caption='RARα-RXRα interaction (PDB entry [[1dkf]])' scene=''> | <StructureSection load='1dq8' size='350' side='left' caption='RARα-RXRα interaction (PDB entry [[1dkf]])' scene=''> | ||
==Ligand Binding Domain== | ==Ligand Binding Domain== | ||
Revision as of 04:03, 7 November 2012
Introduction
T-regulatory cells (T-regs) are a small subset of CD4+ T-cells that exhibit strong down regulation of immune system activity in their local environment. They are distinguished from other CD4+ T-cells by the expression of FOXP3, a gene regulator.
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Biological Significance
References
Proteopedia Page Contributors and Editors (what is this?)
William Bailey, Alexander Berchansky, Michal Harel, Jaime Prilusky
