1pup
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="1pup" size="450" color="white" frame="true" align="right" spinBox="true" caption="1pup, resolution 1.700Å" /> '''CRYSTAL STRUCTURE O...) |
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| - | [[Image:1pup.gif|left|200px]]<br /><applet load="1pup" size=" | + | [[Image:1pup.gif|left|200px]]<br /><applet load="1pup" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1pup, resolution 1.700Å" /> | caption="1pup, resolution 1.700Å" /> | ||
'''CRYSTAL STRUCTURE OF A PEPTIDE NUCLEIC ACID (PNA) DUPLEX AT 1.7 ANGSTROMS RESOLUTION'''<br /> | '''CRYSTAL STRUCTURE OF A PEPTIDE NUCLEIC ACID (PNA) DUPLEX AT 1.7 ANGSTROMS RESOLUTION'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The crystal structure of a PNA duplex reveals both a right- and a | + | The crystal structure of a PNA duplex reveals both a right- and a left-handed helix in the unit cell. The helices are wide (28A), large pitched (18bp) with the base pairs perpendicular to the helix axis, thereby demonstrating that PNA besides adapting to oligonucleotide partners also has a unique structure by itself. |
==About this Structure== | ==About this Structure== | ||
| - | 1PUP is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with NH2 as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http:// | + | 1PUP is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=NH2:'>NH2</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PUP OCA]. |
==Reference== | ==Reference== | ||
Crystal structure of a peptide nucleic acid (PNA) duplex at 1.7 A resolution., Rasmussen H, Kastrup JS, Nielsen JN, Nielsen JM, Nielsen PE, Nat Struct Biol. 1997 Feb;4(2):98-101. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9033585 9033585] | Crystal structure of a peptide nucleic acid (PNA) duplex at 1.7 A resolution., Rasmussen H, Kastrup JS, Nielsen JN, Nielsen JM, Nielsen PE, Nat Struct Biol. 1997 Feb;4(2):98-101. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9033585 9033585] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
| - | [[Category: Kastrup, J | + | [[Category: Kastrup, J S.]] |
[[Category: Rasmussen, H.]] | [[Category: Rasmussen, H.]] | ||
[[Category: NH2]] | [[Category: NH2]] | ||
| Line 19: | Line 19: | ||
[[Category: peptide nucleic acid]] | [[Category: peptide nucleic acid]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:32:43 2008'' |
Revision as of 12:32, 21 February 2008
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CRYSTAL STRUCTURE OF A PEPTIDE NUCLEIC ACID (PNA) DUPLEX AT 1.7 ANGSTROMS RESOLUTION
Overview
The crystal structure of a PNA duplex reveals both a right- and a left-handed helix in the unit cell. The helices are wide (28A), large pitched (18bp) with the base pairs perpendicular to the helix axis, thereby demonstrating that PNA besides adapting to oligonucleotide partners also has a unique structure by itself.
About this Structure
1PUP is a Protein complex structure of sequences from [1] with as ligand. Full crystallographic information is available from OCA.
Reference
Crystal structure of a peptide nucleic acid (PNA) duplex at 1.7 A resolution., Rasmussen H, Kastrup JS, Nielsen JN, Nielsen JM, Nielsen PE, Nat Struct Biol. 1997 Feb;4(2):98-101. PMID:9033585
Page seeded by OCA on Thu Feb 21 14:32:43 2008
