3uxm
From Proteopedia
(Difference between revisions)
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===Structure Guided Development of Novel Thymidine Mimetics targeting Pseudomonas aeruginosa Thymidylate Kinase: from Hit to Lead Generation=== | ===Structure Guided Development of Novel Thymidine Mimetics targeting Pseudomonas aeruginosa Thymidylate Kinase: from Hit to Lead Generation=== | ||
| - | {{ABSTRACT_PUBMED_22243413}} | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3uxm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3uxm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UXM OCA]. |
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:022243413</ref><references group="xtra"/> | <ref group="xtra">PMID:022243413</ref><references group="xtra"/> | ||
| - | [[Category: Pseudomonas aeruginosa]] | + | [[Category: Pseudomonas aeruginosa pao1]] |
[[Category: DTMP kinase]] | [[Category: DTMP kinase]] | ||
[[Category: Chang, J.]] | [[Category: Chang, J.]] | ||
Revision as of 07:06, 14 November 2012
Structure Guided Development of Novel Thymidine Mimetics targeting Pseudomonas aeruginosa Thymidylate Kinase: from Hit to Lead Generation
About this Structure
3uxm is a 4 chain structure with sequence from Pseudomonas aeruginosa pao1. Full crystallographic information is available from OCA.
Reference
- Choi JY, Plummer MS, Starr J, Desbonnet CR, Soutter H, Chang J, Miller JR, Dillman K, Miller AA, Roush WR. Structure Guided Development of Novel Thymidine Mimetics Targeting Pseudomonas aeruginosa Thymidylate Kinase: From Hit to Lead Generation. J Med Chem. 2012 Jan 26;55(2):852-70. Epub 2012 Jan 13. PMID:22243413 doi:10.1021/jm201349f
