1q6y
From Proteopedia
(New page: 200px<br /><applet load="1q6y" size="450" color="white" frame="true" align="right" spinBox="true" caption="1q6y, resolution 1.99Å" /> '''Hypothetical protein...) |
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| - | [[Image:1q6y.gif|left|200px]]<br /><applet load="1q6y" size=" | + | [[Image:1q6y.gif|left|200px]]<br /><applet load="1q6y" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1q6y, resolution 1.99Å" /> | caption="1q6y, resolution 1.99Å" /> | ||
'''Hypothetical protein YfdW from E. coli bound to Coenzyme A'''<br /> | '''Hypothetical protein YfdW from E. coli bound to Coenzyme A'''<br /> | ||
==Overview== | ==Overview== | ||
| - | Crystal structures are reported for free and coenzyme A (CoA) bound forms | + | Crystal structures are reported for free and coenzyme A (CoA) bound forms of the YfdW protein from Escherichia coli, a representative type III CoA transferase. The structures reveal a two-domain protomer with interdomain connections forming a ring-like structure with a large central hole. Two protomers associate to form a highly intertwined dimer in which the hole of each ring is filled by the partner molecule. Each protomer binds a single CoA molecule and these CoA-binding sites are distant from one another in the dimer. |
==About this Structure== | ==About this Structure== | ||
| - | 1Q6Y is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with COA and MPD as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http:// | + | 1Q6Y is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=COA:'>COA</scene> and <scene name='pdbligand=MPD:'>MPD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q6Y OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Burley, S | + | [[Category: Burley, S K.]] |
[[Category: Gogos, A.]] | [[Category: Gogos, A.]] | ||
[[Category: Gorman, J.]] | [[Category: Gorman, J.]] | ||
| - | [[Category: NYSGXRC, New | + | [[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]] |
[[Category: Shapiro, L.]] | [[Category: Shapiro, L.]] | ||
[[Category: COA]] | [[Category: COA]] | ||
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[[Category: structural genomics]] | [[Category: structural genomics]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:36:32 2008'' |
Revision as of 12:36, 21 February 2008
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Hypothetical protein YfdW from E. coli bound to Coenzyme A
Overview
Crystal structures are reported for free and coenzyme A (CoA) bound forms of the YfdW protein from Escherichia coli, a representative type III CoA transferase. The structures reveal a two-domain protomer with interdomain connections forming a ring-like structure with a large central hole. Two protomers associate to form a highly intertwined dimer in which the hole of each ring is filled by the partner molecule. Each protomer binds a single CoA molecule and these CoA-binding sites are distant from one another in the dimer.
About this Structure
1Q6Y is a Single protein structure of sequence from Escherichia coli with and as ligands. Full crystallographic information is available from OCA.
Reference
Structure of Escherichia coli YfdW, a type III CoA transferase., Gogos A, Gorman J, Shapiro L, Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):507-11. Epub 2004, Feb 25. PMID:14993676
Page seeded by OCA on Thu Feb 21 14:36:32 2008
Categories: Escherichia coli | Single protein | Burley, S K. | Gogos, A. | Gorman, J. | NYSGXRC, New York Structural GenomiX Research Consortium. | Shapiro, L. | COA | MPD | Coenzyme a | Intertwined dimer | New york structural genomix research consortium | Nysgxrc | Protein structure initiative | Psi | Structural genomics
