Sandbox Reserved 647
From Proteopedia
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| - | <Structure load='1L8A' size='400' frame='true' align='right' caption='E.coli Pyruvate Dehydrogenase E1 Component' scene='Insert optional scene name here' /> | ||
| - | '''Pyruvate dehydrogenase''' (E1) along with two other enzymes make up the multienzyme complex pyruvate dehydrogenase. Dihydrolipoyl transacetylase (E2) and dihydrolipoyl dehydrogenase (E3) are the other two main components of the complex. These enzymes work together to synthesize acetyl Co-A from pyruvate before entering the Kreb's cycle. The pyruvate dehydrogenase complex acts to link glycolysis to the citric acid cycle. | ||
| - | + | <Structure load='1L8A' size='450' frame='true' align='right' caption='E.coli Pyruvate Dehydrogenase E1 Component' scene='Insert optional scene name here' /> | |
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| + | == Introduction == | ||
| + | '''Pyruvate dehydrogenase''' (E1) along with two other enzymes make up the multienzyme complex pyruvate dehydrogenase. Dihydrolipoyl transacetylase (E2) and dihydrolipoyl dehydrogenase (E3) are the other two main components of the complex. These enzymes work together to synthesize acetyl Co-A from pyruvate before entering the Kreb's cycle. The pyruvate dehydrogenase complex acts to link glycolysis to the citric acid cycle. | ||
| + | [[Image:Pyruvate _ oxidation.jpg | 300 px | thumb | left]] | ||
| + | == Structure == | ||
| + | Pyruvate dehydrogenase <scene name='Sandbox_Reserved_647/Secondary_structure/1'>secondary structure</scene> consists of a combination of beta strands and alpha helices. | ||
| + | == Function == | ||
| + | this is the site of <scene name='Sandbox_Reserved_647/Residue_interaction_with_mg/2'>interaction</scene> between three residues of pyruvate dehydrogenase. | ||
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| - | <Structure load='1ni4' size=' | + | <Structure load='1ni4' size='450' frame='true' align='right' caption='Human Pyruvate Dehydrogenase E1 Component' scene='Insert optional scene name here' /> |
Revision as of 21:30, 14 November 2012
| This Sandbox is Reserved from 30/08/2012, through 01/02/2013 for use in the course "Proteins and Molecular Mechanisms" taught by Robert B. Rose at the North Carolina State University, Raleigh, NC USA. This reservation includes Sandbox Reserved 636 through Sandbox Reserved 685. | ||||||||||||
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IntroductionPyruvate dehydrogenase (E1) along with two other enzymes make up the multienzyme complex pyruvate dehydrogenase. Dihydrolipoyl transacetylase (E2) and dihydrolipoyl dehydrogenase (E3) are the other two main components of the complex. These enzymes work together to synthesize acetyl Co-A from pyruvate before entering the Kreb's cycle. The pyruvate dehydrogenase complex acts to link glycolysis to the citric acid cycle. 
StructurePyruvate dehydrogenase consists of a combination of beta strands and alpha helices.
Functionthis is the site of between three residues of pyruvate dehydrogenase.
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