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Signal recognition particle receptor
From Proteopedia
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| - | <Structure load='2fh5' size='400' frame='true' align='right' caption='Human SRPR α (grey) and β subunit (green) complex with GTP [[2fh5]]' scene= /> | + | <Structure load='2fh5' size='400' frame='true' align='right' caption='Human SRPR α (grey) and β subunit (green) complex with GTP and Mg+2 (green) ion [[2fh5]]' scene= /> |
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Please use the "3D" button above this box to insert a Jmol applet (molecule) on this page. | Please use the "3D" button above this box to insert a Jmol applet (molecule) on this page. | ||
Revision as of 10:14, 15 November 2012
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Signal recognition particle receptor (SRPR) is associated with the endoplasmic reticulum. SRPR is a receptor for the signal recognition particle (SRP). SRPR is a heterodimer with α and β subunits which contain a GTP-binding domain. SRPR α subunit binds to SRP54 subunit of SRP complex. SRPR β subunit is a transmembrane GTPase.
3D structures of SRPR
1nrj – ySRPR α+β subunits + GTP – yeast
2fh5 - hSRPR α+β subunits + GTP – human
2ged - ySRPR β subunit (mutant)
2go5 - hSRPR α subunit + mSRPR β subunit + ribosomal proteins L23, L31, L35 + dSRP19 + dSRP54 + RNA - EM
3dm9, 3dmd, 3e70 – SRPR + GDP – Pyrococcus furiosus
