Transcription initiation factor
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | <StructureSection load='1vol' size='400' side='right' caption='Structure of human TFIIB complex with TATA-binding protein and DNA (PDB entry [[1vol]])' scene=''> | + | <StructureSection load='1vol' size='400' side='right' caption='Structure of human TFIIB (grey) complex with TATA-binding protein (green) and DNA (PDB entry [[1vol]])' scene=''> |
'''Transcription initiation factors''' (TFII) are proteins which enable RNA polymerase II to bind to the DNA template in order to start the transcription process. TFIID recognizes the promoter sequence on the DNA while TFIIB bridges between TFIID and RNA polymerase II. TFIIA is one of several TFs which are required for transcription. TFIIA aids in binding the TATA-binding protein (TBP) to the TATA box containing sequence of the DNA. | '''Transcription initiation factors''' (TFII) are proteins which enable RNA polymerase II to bind to the DNA template in order to start the transcription process. TFIID recognizes the promoter sequence on the DNA while TFIIB bridges between TFIID and RNA polymerase II. TFIIA is one of several TFs which are required for transcription. TFIIA aids in binding the TATA-binding protein (TBP) to the TATA box containing sequence of the DNA. | ||
Revision as of 11:51, 18 November 2012
| |||||||||||
