3vf3

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-	'''Unreleased structure'''	+	[[Image:3vf3.jpg|left|200px]]
-	The entry 3vf3 is ON HOLD until Paper Publication	+	{{STRUCTURE_3vf3| PDB=3vf3 | SCENE= }}
-	Authors: Rondeau, J.M., Bourgier, E.	+	===Crystal Structure of Human Beta Secretase in Complex with NVP-BQQ711===
-	Description: Crystal Structure of Human Beta Secretase in Complex with NVP-BQQ711	+	{{ABSTRACT_PUBMED_22380629}}
		+
		+	==About this Structure==
		+	[[3vf3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VF3 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021388807</ref><references group="xtra"/>
		+	[[Category: Homo sapiens]]
		+	[[Category: Memapsin 2]]
		+	[[Category: Bourgier, E.]]
		+	[[Category: Rondeau, J M.]]
		+	[[Category: Hydrolase-hydrolase inhibitor complex]]
		+	[[Category: Structure-based drug design]]

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Revision as of 09:30, 21 November 2012

Template:STRUCTURE 3vf3

Crystal Structure of Human Beta Secretase in Complex with NVP-BQQ711

Template:ABSTRACT PUBMED 22380629

About this Structure

3vf3 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Rueeger H, Rondeau JM, McCarthy C, Mobitz H, Tintelnot-Blomley M, Neumann U, Desrayaud S. Structure based design, synthesis and SAR of cyclic hydroxyethylamine (HEA) BACE-1 inhibitors. Bioorg Med Chem Lett. 2011 Apr 1;21(7):1942-7. Epub 2011 Feb 15. PMID:21388807 doi:10.1016/j.bmcl.2011.02.038