User:Sruti Aiyaswamy/Sandbox 1
From Proteopedia
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==MR1 is MHC Class I Related== | ==MR1 is MHC Class I Related== | ||
<Structure load='2VAB' size='300' frame='true' align='left' caption='MHC Class I in complex with peptide' scene='' /> Where does this lead? | <Structure load='2VAB' size='300' frame='true' align='left' caption='MHC Class I in complex with peptide' scene='' /> Where does this lead? | ||
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<br>Finally relate how MHC structure/function is similar to MR1. Explain chains, b2m, folding. | <br>Finally relate how MHC structure/function is similar to MR1. Explain chains, b2m, folding. | ||
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<StructureSection load='4GUP' size='500' side='right' caption='Structure of MR1 in complex with b2m and 6-formyl' scene=''> Where does this lead? | <StructureSection load='4GUP' size='500' side='right' caption='Structure of MR1 in complex with b2m and 6-formyl' scene=''> Where does this lead? | ||
</StructureSection> | </StructureSection> | ||
Revision as of 07:52, 27 November 2012
Introduction
The MHC class I-like molecule, MR1, is an antigen presenting protein that specifically activates mucosal-associated invariant T (MAIT) cells. It has been found that microbial vitamin B metabolites serve as MR1 ligands that activate the MAIT cells.
MR1 is MHC Class I Related
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Finally relate how MHC structure/function is similar to MR1. Explain chains, b2m, folding.
Structure of MR1-antigen Complex
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