1jm7
From Proteopedia
(Difference between revisions)
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[[Image:1jm7.png|left|200px]] | [[Image:1jm7.png|left|200px]] | ||
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{{STRUCTURE_1jm7| PDB=1jm7 | SCENE= }} | {{STRUCTURE_1jm7| PDB=1jm7 | SCENE= }} | ||
===Solution structure of the BRCA1/BARD1 RING-domain heterodimer=== | ===Solution structure of the BRCA1/BARD1 RING-domain heterodimer=== | ||
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{{ABSTRACT_PUBMED_11573085}} | {{ABSTRACT_PUBMED_11573085}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Breast cancer-1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Breast-ovarian cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Ovarian cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Papillary serous carcinoma of the peritoneum OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Breast cancer, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601593 601593]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1jm7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JM7 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:011573085</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Brzovic, P S.]] | [[Category: Brzovic, P S.]] | ||
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[[Category: Klevit, R E.]] | [[Category: Klevit, R E.]] | ||
[[Category: Rajagopal, P.]] | [[Category: Rajagopal, P.]] | ||
| + | [[Category: Antitumor]] | ||
[[Category: Bard1]] | [[Category: Bard1]] | ||
[[Category: Brca1]] | [[Category: Brca1]] | ||
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[[Category: Ubiquitin ligase]] | [[Category: Ubiquitin ligase]] | ||
[[Category: Zinc-binding protein]] | [[Category: Zinc-binding protein]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:10:38 2009'' | ||
Revision as of 11:20, 5 December 2012
Solution structure of the BRCA1/BARD1 RING-domain heterodimer
Template:ABSTRACT PUBMED 11573085
About this Structure
1jm7 is a 2 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
Reference
- Brzovic PS, Rajagopal P, Hoyt DW, King MC, Klevit RE. Structure of a BRCA1-BARD1 heterodimeric RING-RING complex. Nat Struct Biol. 2001 Oct;8(10):833-7. PMID:11573085 doi:10.1038/nsb1001-833
