1kar

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Revision as of 20:23, 5 December 2012

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spinqualitylabelsall models PDB ID 1kar Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
1kar, resolution 2.10Å ()
Ligands:	,
Non-Standard Residues:
Gene:	HISD (Escherichia coli)
Activity:	Histidinol dehydrogenase, with EC number 1.1.1.23
Related:	1k75, 1kae, 1kah
Structural annotation: Resources: CATH : 1Kara02, 1Kara01, 1Karb01, 1Karb02 InterPro : Ipr012131, Ipr001692 Pfam : PF00815 SCOP : d1kara_, d1karb_ UniProt : P06988
Functional annotation: Biological process: histidine biosynthetic process amino acid biosynthetic process Molecular function: metal ion binding NAD binding histidinol dehydrogenase activity oxidoreductase activity zinc ion binding
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

L-HISTIDINOL DEHYDROGENASE (HISD) STRUCTURE COMPLEXED WITH HISTAMINE (INHIBITOR), ZINC AND NAD (COFACTOR)

Template:ABSTRACT PUBMED 11842181

About this Structure

1kar is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

• Barbosa JA, Sivaraman J, Li Y, Larocque R, Matte A, Schrag JD, Cygler M. Mechanism of action and NAD+-binding mode revealed by the crystal structure of L-histidinol dehydrogenase. Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1859-64. Epub 2002 Feb 12. PMID:11842181 doi:10.1073/pnas.022476199