1nc6

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Image:1nc6.png

Template:STRUCTURE 1nc6

Potent, small molecule inhibitors of human mast cell tryptase. Anti-asthmatic action of a dipeptide-based transition state analogue containing benzothiazole ketone

Template:ABSTRACT PUBMED 12930148

About this Structure

1nc6 is a 1 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Costanzo MJ, Yabut SC, Almond HR Jr, Andrade-Gordon P, Corcoran TW, De Garavilla L, Kauffman JA, Abraham WM, Recacha R, Chattopadhyay D, Maryanoff BE. Potent, small-molecule inhibitors of human mast cell tryptase. Antiasthmatic action of a dipeptide-based transition-state analogue containing a benzothiazole ketone. J Med Chem. 2003 Aug 28;46(18):3865-76. PMID:12930148 doi:http://dx.doi.org/10.1021/jm030050p

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OCA

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