1nys
From Proteopedia
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===Crystal Structure of Activin A Bound to the ECD of ActRIIB P41=== | ===Crystal Structure of Activin A Bound to the ECD of ActRIIB P41=== | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | [[1nys]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NYS OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012660162</ref><ref group="xtra">PMID:017295905</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
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[[Category: Actriib]] | [[Category: Actriib]] | ||
[[Category: Extracellular domain]] | [[Category: Extracellular domain]] | ||
| + | [[Category: Membrane protein-hormone-growth factor complex]] | ||
[[Category: Tgf beta]] | [[Category: Tgf beta]] | ||
[[Category: Type ii]] | [[Category: Type ii]] | ||
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Revision as of 20:59, 5 December 2012
Crystal Structure of Activin A Bound to the ECD of ActRIIB P41
Template:ABSTRACT PUBMED 12660162
About this Structure
1nys is a 4 chain structure with sequence from Homo sapiens and Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Thompson TB, Woodruff TK, Jardetzky TS. Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions. EMBO J. 2003 Apr 1;22(7):1555-66. PMID:12660162 doi:10.1093/emboj/cdg156
- Weber D, Kotzsch A, Nickel J, Harth S, Seher A, Mueller U, Sebald W, Mueller TD. A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor. BMC Struct Biol. 2007 Feb 12;7:6. PMID:17295905 doi:10.1186/1472-6807-7-6
