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1s22
From Proteopedia
(New page: 200px<br /><applet load="1s22" size="450" color="white" frame="true" align="right" spinBox="true" caption="1s22, resolution 1.60Å" /> '''Absolute Stereochemi...) |
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| - | [[Image:1s22.gif|left|200px]]<br /><applet load="1s22" size=" | + | [[Image:1s22.gif|left|200px]]<br /><applet load="1s22" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1s22, resolution 1.60Å" /> | caption="1s22, resolution 1.60Å" /> | ||
'''Absolute Stereochemistry of Ulapualide A'''<br /> | '''Absolute Stereochemistry of Ulapualide A'''<br /> | ||
==Overview== | ==Overview== | ||
| - | [structure: see text] The structure of ulapualide A (1) has been solved by | + | [structure: see text] The structure of ulapualide A (1) has been solved by X-ray crystallography in a complex with G-actin. The stereochemical configuration was assigned as 3S,9S,22S,23R,24S,26S,27S,31R,32R,33R. |
==About this Structure== | ==About this Structure== | ||
| - | 1S22 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus] with CA, ATP, ULA and EDO as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http:// | + | 1S22 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus] with <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=ATP:'>ATP</scene>, <scene name='pdbligand=ULA:'>ULA</scene> and <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S22 OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Oryctolagus cuniculus]] | [[Category: Oryctolagus cuniculus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Allingham, J | + | [[Category: Allingham, J S.]] |
[[Category: Marriott, G.]] | [[Category: Marriott, G.]] | ||
[[Category: Rayment, I.]] | [[Category: Rayment, I.]] | ||
| Line 23: | Line 23: | ||
[[Category: actin; trisoxazole; macrolide; toxin; ulapualide; stereochemistry]] | [[Category: actin; trisoxazole; macrolide; toxin; ulapualide; stereochemistry]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:57:03 2008'' |
Revision as of 12:57, 21 February 2008
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Absolute Stereochemistry of Ulapualide A
Overview
[structure: see text] The structure of ulapualide A (1) has been solved by X-ray crystallography in a complex with G-actin. The stereochemical configuration was assigned as 3S,9S,22S,23R,24S,26S,27S,31R,32R,33R.
About this Structure
1S22 is a Single protein structure of sequence from Oryctolagus cuniculus with , , and as ligands. Full crystallographic information is available from OCA.
Reference
Absolute stereochemistry of ulapualide A., Allingham JS, Tanaka J, Marriott G, Rayment I, Org Lett. 2004 Feb 19;6(4):597-9. PMID:14961632
Page seeded by OCA on Thu Feb 21 14:57:03 2008
