CD44

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'''CD44''' is a glycoprotein involved in cell-cell interactions. CD44 is a receptor of hyaluronic acid (HA). CD44 undergoes post-translational modification. Its sialofucosylation changes it to a form which directs migration of stem cells to bone marrow.
'''CD44''' is a glycoprotein involved in cell-cell interactions. CD44 is a receptor of hyaluronic acid (HA). CD44 undergoes post-translational modification. Its sialofucosylation changes it to a form which directs migration of stem cells to bone marrow.
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==3D structures of CD44==
[[1uuh]] – hCD44 hyaluronan-binding domain – human<br />
[[1uuh]] – hCD44 hyaluronan-binding domain – human<br />

Revision as of 13:05, 12 December 2012

Structure of mouse CD44 hyaluronan-binding domain complex with 8-mer HA (PDB entry 2jcq)

Drag the structure with the mouse to rotate

CD44 is a glycoprotein involved in cell-cell interactions. CD44 is a receptor of hyaluronic acid (HA). CD44 undergoes post-translational modification. Its sialofucosylation changes it to a form which directs migration of stem cells to bone marrow.

3D structures of CD44

1uuh – hCD44 hyaluronan-binding domain – human
1poz, 2i83 - hCD44 hyaluronan-binding domain – NMR
2jcp - mCD44 hyaluronan-binding domain – mouse
2jcq, 2jcr - mCD44 hyaluronan-binding domain + 8-mer HA

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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