Hormone
From Proteopedia
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===Adrenaline=== | ===Adrenaline=== | ||
[[Beta-2 Adrenergic Receptor]]<br /> | [[Beta-2 Adrenergic Receptor]]<br /> | ||
| - | [[Adrenergic receptor]]<br /> | + | The human β2 adrenergic receptor bound to a G-protein ([[3sn6]]) and [[hormone]] analog is featured in an image on the right, and additional structures are on the [[Adrenergic receptor|Adrenergic receptor page]]. <br /> |
===Angiotensinogen=== | ===Angiotensinogen=== | ||
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===Growth Hormone=== | ===Growth Hormone=== | ||
| + | [[Image:7tm labeled.png|right|400px]] | ||
[[3hhr]] - Growth Hormone complexed with the extracellular portion of its receptor - human<br /> | [[3hhr]] - Growth Hormone complexed with the extracellular portion of its receptor - human<br /> | ||
[[1hwh]] - Growth Hormone Mutant G120R complexed with the extracellular portion of its receptor - human<br /> | [[1hwh]] - Growth Hormone Mutant G120R complexed with the extracellular portion of its receptor - human<br /> | ||
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* [[Membrane proteins]] | * [[Membrane proteins]] | ||
* [[G protein-coupled receptor|G protein-coupled receptors]] | * [[G protein-coupled receptor|G protein-coupled receptors]] | ||
| + | * [[Nobel Prizes for 3D Molecular Structure]] | ||
| + | * [[Highest impact structures]] of all time | ||
Revision as of 23:47, 15 December 2012
In the field of modern endocrinology, a hormone is any substance, generated either externally or internally, that operates via a receptor at the cellular level, which conveys to to the cell a message to stop, start, or modulate a cellular process.
Guide to Proteopedia Pages Concerning Hormones and their Receptors
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| FSH binding to the leucine-rich domain of Follicle Stimulating Hormone Receptor (1fl7 morphing to 1xwd, resolution 2.92Å) | |||||||
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Articles in Proteopedia concerning Hormone include:
To view automatically seeded indices concerning Hormone, see:
Additional 3D Structures of Hormones and Hormone Receptors and Related Molecules
Adrenaline
Beta-2 Adrenergic Receptor
The human β2 adrenergic receptor bound to a G-protein (3sn6) and hormone analog is featured in an image on the right, and additional structures are on the Adrenergic receptor page.
Angiotensinogen
2wxw, 2wxx, 2wxy, 2wxz, 2wy0, 2wy1, 2x0b - Angiotensinogen – human, rat, mouse
Chorionic Gonadotropin
1hrp - Chorionic Gonadotropin – human
1hcn - Chorionic Gonadotropin – human
1hd4 - Alpha-subunit of Chorionic Gonadotropin – human
Follicle-Stimulating Hormone
1fl7 - Follicle-Stimulating Hormone – human
1xwd - Human Follicle Stimulating Hormone complexed with its Receptor – human
Glucocorticoid
3mne, 3mno, 3mnp - Glucocorticoid Receptor Ligand-binding Domain – human
Glucose-dependent Insulinotropic Polypeptide
Glucose-dependent Insulinotropic Polypeptide Receptor
Growth Hormone
3hhr - Growth Hormone complexed with the extracellular portion of its receptor - human
1hwh - Growth Hormone Mutant G120R complexed with the extracellular portion of its receptor - human
1bp3 - Growth Hormone complexed with the prolactin receptor - human
3mjg, 3mjk - Platelet-derived Growth Factor/Propeptide Complex and a Platelet-Derived Growth Factor/Receptor Complex – human
Vascular Endothelial Growth Factor – human and others, see Vascular Endothelial Growth Factor Structures
Vascular Endothelial Growth Factor Receptor – human, see Vascular Endothelial Growth Factor Receptor Structures
2xdg - Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor – human
Insulin
3ir0 , 1mso , 1trz , 2qiu , 2r34, 2r35 , 2r36, 3ilg, 2kjj , 2kju - Insulin – human
3nw5, 3nw6, 3nw7 - insulin-like growth factor 1 receptor – human
3loh, 2dtg - insulin receptor ectodomain – human
Glucose-dependent Insulinotropic Polypeptide Receptor
Progesterone
3hq5,3g8n, 3g8o, 3hq5 - Progesterone – human
Thyroid-Stimulating hormone
3g04 - TSH receptor in complex with a thyroid-stimulating autoantibody – human
Thyroid hormone
2nll - DNA-Binding domain in complex with an inverted repeat class of thyroid response element– rat
1xzx
Thyroxine
2xn3, 2xn5, 2xn6, 2xn7 - Thyroxine-binding Globulin – human
Farnesoid X Receptor
3olf, 3omk, 3omm, 3oof, 3ook, 3okh, 3oki - Farnesoid X Receptor – human
PACAP/glucagon family of peptide hormones
3n94 - PAC1R, receptor of pituitary adenylate cyclase activating polypeptide, is a case of a crystal structure disagreeing with the NMR structure 2jod and vice versa
2jod - Pituitary adenylate cyclase-activating polypeptide (residues 6'-38') complexed to the extracellular domain of the human splice variant hPAC1-RS determined by NMR - human
Estrogen-related receptor
Estrogen-related recepto – human and others, see Estrogen-related receptor structures
ADD 3dzu
See Also
- Cancer
- Membrane proteins
- G protein-coupled receptors
- Nobel Prizes for 3D Molecular Structure
- Highest impact structures of all time
External Resources
- Sequence-Structure-Function-Analysis of Glycoprotein Hormone Receptors
- GRIS: Glycoprotein-hormone Receptors Information System
- The GPCR-SSFE Database: A Homology Model Resource for G-Protein Coupled Receptors
- The feature on Growth Hormone by Shuchismita Dutta and David S. Goodsell for the April 2004 RCSB PDB Molecule of the Month.
- NeuroPedia, a neuropeptide database and spectral library
Proteopedia Page Contributors and Editors (what is this?)
Wayne Decatur, Alexander Berchansky, Michal Harel, Tomas Klumpler, Joel L. Sussman
