User:Johanna Spaniol/Sandbox 1
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(New page: <Structure load='2ljr' size='500' frame='true' align='right' caption='Insert caption here' scene='Insert optional scene name here' /> Glutathione S-Transferase form a wide family of enzym...)
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Revision as of 13:33, 18 December 2012
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Glutathione S-Transferase form a wide family of enzymes divided in mammals into 5 classes (alpha, mu, pi, sigma and theta). These enzymes are involved in the cellular detoxification : they reduce the reactivity of toxic compounds by catalysing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents (green link). Gluthathione theta class S-Transferase is an enzyme member of the GTS family, located in hepatic cells of procaryotes and eucaryotes in the cytosol and in mitochondrias. This enzyme is a dimeric protein of 45-55kDa.