1sp3
From Proteopedia
(New page: 200px<br /><applet load="1sp3" size="450" color="white" frame="true" align="right" spinBox="true" caption="1sp3, resolution 2.20Å" /> '''Crystal structure of...) |
|||
| Line 1: | Line 1: | ||
| - | [[Image:1sp3.jpg|left|200px]]<br /><applet load="1sp3" size=" | + | [[Image:1sp3.jpg|left|200px]]<br /><applet load="1sp3" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1sp3, resolution 2.20Å" /> | caption="1sp3, resolution 2.20Å" /> | ||
'''Crystal structure of octaheme cytochrome c from Shewanella oneidensis'''<br /> | '''Crystal structure of octaheme cytochrome c from Shewanella oneidensis'''<br /> | ||
==Overview== | ==Overview== | ||
| - | We have isolated a soluble cytochrome from Shewanella oneidensis that | + | We have isolated a soluble cytochrome from Shewanella oneidensis that contains eight covalently attached heme groups and determined its crystal structure. One of these hemes exhibits novel ligation of the iron atom by the epsilon-amino group of a lysine residue, despite its attachment via a typical CXXCH motif. This heme is most likely the active site for tetrathionate reduction, a reaction catalyzed efficiently by this enzyme. |
==About this Structure== | ==About this Structure== | ||
| - | 1SP3 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacteria Bacteria] with SCN and HEM as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http:// | + | 1SP3 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bacteria Bacteria] with <scene name='pdbligand=SCN:'>SCN</scene> and <scene name='pdbligand=HEM:'>HEM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SP3 OCA]. |
==Reference== | ==Reference== | ||
| Line 13: | Line 13: | ||
[[Category: Bacteria]] | [[Category: Bacteria]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Chapman, S | + | [[Category: Chapman, S K.]] |
| - | [[Category: Doherty, M | + | [[Category: Doherty, M K.]] |
[[Category: Drewette, K.]] | [[Category: Drewette, K.]] | ||
[[Category: McIver, L.]] | [[Category: McIver, L.]] | ||
| - | [[Category: Miles, C | + | [[Category: Miles, C S.]] |
| - | [[Category: Mowat, C | + | [[Category: Mowat, C G.]] |
| - | [[Category: Reid, G | + | [[Category: Reid, G A.]] |
[[Category: Rothery, E.]] | [[Category: Rothery, E.]] | ||
[[Category: Taylor, P.]] | [[Category: Taylor, P.]] | ||
| - | [[Category: Walkinshaw, M | + | [[Category: Walkinshaw, M D.]] |
[[Category: HEM]] | [[Category: HEM]] | ||
[[Category: SCN]] | [[Category: SCN]] | ||
| Line 28: | Line 28: | ||
[[Category: octaheme]] | [[Category: octaheme]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:03:46 2008'' |
Revision as of 13:03, 21 February 2008
|
Crystal structure of octaheme cytochrome c from Shewanella oneidensis
Overview
We have isolated a soluble cytochrome from Shewanella oneidensis that contains eight covalently attached heme groups and determined its crystal structure. One of these hemes exhibits novel ligation of the iron atom by the epsilon-amino group of a lysine residue, despite its attachment via a typical CXXCH motif. This heme is most likely the active site for tetrathionate reduction, a reaction catalyzed efficiently by this enzyme.
About this Structure
1SP3 is a Single protein structure of sequence from Bacteria with and as ligands. Full crystallographic information is available from OCA.
Reference
Octaheme tetrathionate reductase is a respiratory enzyme with novel heme ligation., Mowat CG, Rothery E, Miles CS, McIver L, Doherty MK, Drewette K, Taylor P, Walkinshaw MD, Chapman SK, Reid GA, Nat Struct Mol Biol. 2004 Oct;11(10):1023-4. Epub 2004 Sep 7. PMID:15361860
Page seeded by OCA on Thu Feb 21 15:03:46 2008
Categories: Bacteria | Single protein | Chapman, S K. | Doherty, M K. | Drewette, K. | McIver, L. | Miles, C S. | Mowat, C G. | Reid, G A. | Rothery, E. | Taylor, P. | Walkinshaw, M D. | HEM | SCN | Cytochrome c | Octaheme
