1p4r
From Proteopedia
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[[Image:1p4r.png|left|200px]] | [[Image:1p4r.png|left|200px]] | ||
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{{STRUCTURE_1p4r| PDB=1p4r | SCENE= }} | {{STRUCTURE_1p4r| PDB=1p4r | SCENE= }} | ||
===Crystal Structure of Human ATIC in complex with folate-based inhibitor BW1540U88UD=== | ===Crystal Structure of Human ATIC in complex with folate-based inhibitor BW1540U88UD=== | ||
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{{ABSTRACT_PUBMED_14966129}} | {{ABSTRACT_PUBMED_14966129}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1p4r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P4R OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:014966129</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Beardsley, G P.]] | [[Category: Beardsley, G P.]] | ||
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[[Category: Atic]] | [[Category: Atic]] | ||
[[Category: Bw1540u88ud]] | [[Category: Bw1540u88ud]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Purine biosynthesis]] | [[Category: Purine biosynthesis]] | ||
| - | + | [[Category: Transferase]] | |
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Revision as of 11:47, 19 December 2012
Crystal Structure of Human ATIC in complex with folate-based inhibitor BW1540U88UD
Template:ABSTRACT PUBMED 14966129
About this Structure
1p4r is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Cheong CG, Wolan DW, Greasley SE, Horton PA, Beardsley GP, Wilson IA. Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates. J Biol Chem. 2004 Apr 23;279(17):18034-45. Epub 2004 Feb 13. PMID:14966129 doi:10.1074/jbc.M313691200
