1pkx
From Proteopedia
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===Crystal Structure of human ATIC in complex with XMP=== | ===Crystal Structure of human ATIC in complex with XMP=== | ||
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{{ABSTRACT_PUBMED_14756553}} | {{ABSTRACT_PUBMED_14756553}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: AICA-ribosiduria due to ATIC deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601731 601731]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1pkx]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PKX OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:014756553</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Cheong, C G.]] | [[Category: Cheong, C G.]] | ||
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[[Category: Aicar transformylase]] | [[Category: Aicar transformylase]] | ||
[[Category: Atic]] | [[Category: Atic]] | ||
| + | [[Category: Hydrolase]] | ||
[[Category: Imp cyclohydrolase]] | [[Category: Imp cyclohydrolase]] | ||
[[Category: Purine biosynthesis]] | [[Category: Purine biosynthesis]] | ||
| + | [[Category: Transferase]] | ||
[[Category: Xanthosine monophosphate]] | [[Category: Xanthosine monophosphate]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 19:13:42 2009'' | ||
Revision as of 11:49, 19 December 2012
Crystal Structure of human ATIC in complex with XMP
Template:ABSTRACT PUBMED 14756553
About this Structure
1pkx is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wolan DW, Cheong CG, Greasley SE, Wilson IA. Structural insights into the human and avian IMP cyclohydrolase mechanism via crystal structures with the bound XMP inhibitor. Biochemistry. 2004 Feb 10;43(5):1171-83. PMID:14756553 doi:10.1021/bi030162i
