1pv8
From Proteopedia
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[[Image:1pv8.png|left|200px]] | [[Image:1pv8.png|left|200px]] | ||
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{{STRUCTURE_1pv8| PDB=1pv8 | SCENE= }} | {{STRUCTURE_1pv8| PDB=1pv8 | SCENE= }} | ||
===Crystal structure of a low activity F12L mutant of human porphobilinogen synthase=== | ===Crystal structure of a low activity F12L mutant of human porphobilinogen synthase=== | ||
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{{ABSTRACT_PUBMED_12897770}} | {{ABSTRACT_PUBMED_12897770}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Porphyria, acute hepatic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=125270 125270]], Lead poisoning, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=125270 125270]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1pv8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PV8 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:012897770</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Porphobilinogen synthase]] | [[Category: Porphobilinogen synthase]] | ||
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[[Category: Reaction intermediate]] | [[Category: Reaction intermediate]] | ||
[[Category: Tetrapyrrole biosynthesis]] | [[Category: Tetrapyrrole biosynthesis]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 2 08:24:50 2010'' | ||
Revision as of 11:57, 19 December 2012
Crystal structure of a low activity F12L mutant of human porphobilinogen synthase
Template:ABSTRACT PUBMED 12897770
About this Structure
1pv8 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Breinig S, Kervinen J, Stith L, Wasson AS, Fairman R, Wlodawer A, Zdanov A, Jaffe EK. Control of tetrapyrrole biosynthesis by alternate quaternary forms of porphobilinogen synthase. Nat Struct Biol. 2003 Sep;10(9):757-63. Epub 2003 Aug 3. PMID:12897770 doi:10.1038/nsb963
