Sandbox UC 11

(Difference between revisions)

Revision as of 20:04, 19 December 2012

Structural annotation:
Resources:	CATH : 1Mnmc00, 1Mnmd00 InterPro : Ipr002100, Ipr001356, Ipr012287, Ipr009057 Pfam : PF00319, PF00046 SCOP : d1mnma_, d1mnmb_, d1mnmc_, d1mnmd_ UniProt : P11746, Q6B2C0

Functional annotation:
Cellular component:	nuclear chromatin nucleus
Biological process:	regulation of transcription from RNA polymerase II promoter cell cycle transcription DNA replication initiation regulation of transcription, DNA-dependent donor selection regulation of transcription
Molecular function:	DNA bending activity sequence-specific DNA binding transcription factor activity DNA replication origin binding DNA binding

Evolutionary conservation:

Toggle Conservation Colors:

Rows = identical sequences:

Further Information:

Caveats,

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

YEAST MATALPHA2/MCM1/DNA TERNARY TRANSCRIPTION COMPLEX CRYSTAL STRUCTURE (PDB entry 1mnm)

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Kleanthous C, Kuhlmann UC, Pommer AJ, Ferguson N, Radford SE, Moore GR, James R, Hemmings AM. Structural and mechanistic basis of immunity toward endonuclease colicins. Nat Struct Biol. 1999 Mar;6(3):243-52. PMID:10074943 doi:http://dx.doi.org/10.1038/6683
Levin KB, Dym O, Albeck S, Magdassi S, Keeble AH, Kleanthous C, Tawfik DS. Following evolutionary paths to protein-protein interactions with high affinity and selectivity. Nat Struct Mol Biol. 2009 Oct;16(10):1049-55. Epub 2009 Sep 13. PMID:19749752 doi:10.1038/nsmb.1670

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+[[Image:Cyt_trim.jpg|left|150px]]
+{{STRUCTURE_2rci|  PDB=2rci  |  SCENE=Cyt2Ba/Cartoon_spectrum/2  }}
 {{STRUCTURE_1mnm}}
 <StructureSection load='1mnm' size='350' side='right' caption='YEAST MATALPHA2/MCM1/DNA TERNARY TRANSCRIPTION COMPLEX CRYSTAL STRUCTURE (PDB entry [[1mnm]])' scene=''>