1szy
From Proteopedia
(New page: 200px<br /><applet load="1szy" size="450" color="white" frame="true" align="right" spinBox="true" caption="1szy" /> '''Solution structure of ITALY1 ("Initiator tRN...) |
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| - | [[Image:1szy.gif|left|200px]]<br /><applet load="1szy" size=" | + | [[Image:1szy.gif|left|200px]]<br /><applet load="1szy" size="350" color="white" frame="true" align="right" spinBox="true" |
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'''Solution structure of ITALY1 ("Initiator tRNA Anticodon Loop from Yeast"), an unmodified 21-nt RNA with the sequence of the anticodon stem-loop of yeast initiator tRNA'''<br /> | '''Solution structure of ITALY1 ("Initiator tRNA Anticodon Loop from Yeast"), an unmodified 21-nt RNA with the sequence of the anticodon stem-loop of yeast initiator tRNA'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The solution conformations of analogues of initiator and elongator tRNA | + | The solution conformations of analogues of initiator and elongator tRNA anticodon stem-loops have been compared by NMR. The data indicate that both have conformations closely similar to those reported for crystalline elongator tRNAs. The two loops differ in their dynamics, however: that of the elongator analogue is more flexible than its initiator counterpart. The anticodon stem-loops of initiator tRNAs are more likely to be distinguished from those of elongator tRNAs during initiation on the basis of their distinctive stem sequences, than they are by differences in the conformations of their anticodon loops. |
==About this Structure== | ==About this Structure== | ||
| - | 1SZY is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http:// | + | 1SZY is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZY OCA]. |
==Reference== | ==Reference== | ||
On the conformation of the anticodon loops of initiator and elongator methionine tRNAs., Schweisguth DC, Moore PB, J Mol Biol. 1997 Apr 4;267(3):505-19. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9126834 9126834] | On the conformation of the anticodon loops of initiator and elongator methionine tRNAs., Schweisguth DC, Moore PB, J Mol Biol. 1997 Apr 4;267(3):505-19. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9126834 9126834] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
| - | [[Category: Moore, P | + | [[Category: Moore, P B.]] |
| - | [[Category: Schweisguth, D | + | [[Category: Schweisguth, D C.]] |
[[Category: initiator trna anticodon loop]] | [[Category: initiator trna anticodon loop]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:08:08 2008'' |
Revision as of 13:08, 21 February 2008
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Solution structure of ITALY1 ("Initiator tRNA Anticodon Loop from Yeast"), an unmodified 21-nt RNA with the sequence of the anticodon stem-loop of yeast initiator tRNA
Overview
The solution conformations of analogues of initiator and elongator tRNA anticodon stem-loops have been compared by NMR. The data indicate that both have conformations closely similar to those reported for crystalline elongator tRNAs. The two loops differ in their dynamics, however: that of the elongator analogue is more flexible than its initiator counterpart. The anticodon stem-loops of initiator tRNAs are more likely to be distinguished from those of elongator tRNAs during initiation on the basis of their distinctive stem sequences, than they are by differences in the conformations of their anticodon loops.
About this Structure
1SZY is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
On the conformation of the anticodon loops of initiator and elongator methionine tRNAs., Schweisguth DC, Moore PB, J Mol Biol. 1997 Apr 4;267(3):505-19. PMID:9126834
Page seeded by OCA on Thu Feb 21 15:08:08 2008
