Sandbox Reserved 704
From Proteopedia
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| - | < | + | == Crystal structure of leucyl-tRNA synthetase and tRNA (leucine) complex == |
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| + | Aminoacyl-tRNA synthetases are ligases which exclusively attach a particular amino acid to the 3’ of its set of cognate tRNAs isoacceptors. It is a two-step reaction: First, an activated intermediate called aminoacyladenylate is synthesized from the amino acid and ATP. Then, the activated amino acid is transferred to the 3’-end of the tRNA. It leads to the formation of the aminoacyl-tRNA. The fidelity of protein synthesis depends of the accuracy of this reaction. | ||
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| + | <StructureSection load='1wz2' size='350' side='right' caption='(PDB entry [[1wz2]])' scene=''> | ||
Revision as of 14:28, 29 December 2012
Crystal structure of leucyl-tRNA synthetase and tRNA (leucine) complex
Aminoacyl-tRNA synthetases are ligases which exclusively attach a particular amino acid to the 3’ of its set of cognate tRNAs isoacceptors. It is a two-step reaction: First, an activated intermediate called aminoacyladenylate is synthesized from the amino acid and ATP. Then, the activated amino acid is transferred to the 3’-end of the tRNA. It leads to the formation of the aminoacyl-tRNA. The fidelity of protein synthesis depends of the accuracy of this reaction.
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