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From Proteopedia
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== STRUCTURE OF THE RECEPTOR-BINDING DOMAIN OF THE BACTERIOPHAGE T4 SHORT TAIL FIBRE== | == STRUCTURE OF THE RECEPTOR-BINDING DOMAIN OF THE BACTERIOPHAGE T4 SHORT TAIL FIBRE== | ||
| - | The T4 bacteriophage is a virus which affects ''Escherichia coli''. To adsorb to its host cell the T4 bacteriophage uses six long and six short tail fibres. The first adsorption stage is the initial and reversible binding of the long tail fibres to the protein C (OmpC) or to the lipo-polysaccharide (LPS), which are located in the outer membrane of ''Escherichia coli''. At least three long tail fibres have to bind before the short tail fibres can bind.After at least three long tail fibres have bound, the baseplate changes its conformation and the short tail fibres bind irreversible to the core region of the host cell LPS. Short tail fibres consist of a single protein. This protein is 1ocy it forms a parallel, in-register, homo-trimer of 527 residues per subunit. | + | The T4 bacteriophage is a virus which affects ''Escherichia coli''. To adsorb to its host cell the T4 bacteriophage uses six long and six short tail fibres. The first adsorption stage is the initial and reversible binding of the long tail fibres to the protein C (OmpC) or to the lipo-polysaccharide (LPS), which are located in the outer membrane of ''Escherichia coli''. At least three long tail fibres have to bind before the short tail fibres can bind.After at least three long tail fibres have bound, the baseplate changes its conformation and the short tail fibres bind irreversible to the core region of the host cell LPS. Short tail fibres consist of a single protein. This protein is gene product 12 (gp12;its PDB name is 1ocy) it forms a parallel, in-register, homo-trimer of 527 residues per subunit. |
== Description == | == Description == | ||
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== Structure == | == Structure == | ||
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| + | == References == | ||
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| + | == Contributors == | ||
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| + | Anne-Lise Terrier, Bianca Waßmer | ||
Revision as of 21:37, 29 December 2012
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Contents |
STRUCTURE OF THE RECEPTOR-BINDING DOMAIN OF THE BACTERIOPHAGE T4 SHORT TAIL FIBRE
The T4 bacteriophage is a virus which affects Escherichia coli. To adsorb to its host cell the T4 bacteriophage uses six long and six short tail fibres. The first adsorption stage is the initial and reversible binding of the long tail fibres to the protein C (OmpC) or to the lipo-polysaccharide (LPS), which are located in the outer membrane of Escherichia coli. At least three long tail fibres have to bind before the short tail fibres can bind.After at least three long tail fibres have bound, the baseplate changes its conformation and the short tail fibres bind irreversible to the core region of the host cell LPS. Short tail fibres consist of a single protein. This protein is gene product 12 (gp12;its PDB name is 1ocy) it forms a parallel, in-register, homo-trimer of 527 residues per subunit.
Description
Structure
References
Contributors
Anne-Lise Terrier, Bianca Waßmer
