Sandbox Reserved 708
From Proteopedia
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== Activity == | == Activity == | ||
| - | Phosphorylation at <scene name='Sandbox_Reserved_708/Phosphorylated_amino_acids/1'>tyrosine-216 in GSK-3β or tyrosine-279</scene> in GSK-3α enhances the enzymatic activity of GSK-3, while phosphorlyation of serine-9 in GSK-3β or serine-21 in GSK-3α significantly decreases active site availability | + | Phosphorylation at <scene name='Sandbox_Reserved_708/Phosphorylated_amino_acids/1'> tyrosine-216 in GSK-3β or tyrosine-279</scene> in GSK-3α enhances the enzymatic activity of GSK-3, while phosphorlyation of serine-9 in GSK-3β or serine-21 in GSK-3α significantly decreases active site availability |
== Structure == | == Structure == | ||
Revision as of 18:21, 30 December 2012
Contents |
Descritpion
Activity
Phosphorylation at in GSK-3α enhances the enzymatic activity of GSK-3, while phosphorlyation of serine-9 in GSK-3β or serine-21 in GSK-3α significantly decreases active site availability
Structure
These are the engaged in the catalytic site of the protein, they are polar and localised in 3' end (Asp-181, Lys-183, Gln-185, Asn-186 and Ser-219. The Tau protein possesses as well as (Adenosine DiPhosphate) This enzyme is activated by phosphorylation at .
