1t3p
From Proteopedia
(New page: 200px<br /><applet load="1t3p" size="450" color="white" frame="true" align="right" spinBox="true" caption="1t3p, resolution 1.60Å" /> '''Half-sandwich arene ...) |
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| - | [[Image:1t3p.gif|left|200px]]<br /><applet load="1t3p" size=" | + | [[Image:1t3p.gif|left|200px]]<br /><applet load="1t3p" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1t3p, resolution 1.60Å" /> | caption="1t3p, resolution 1.60Å" /> | ||
'''Half-sandwich arene ruthenium(II)-enzyme complex'''<br /> | '''Half-sandwich arene ruthenium(II)-enzyme complex'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The 1.6 [Angstrom] X-ray crystal structure of | + | The 1.6 [Angstrom] X-ray crystal structure of [(eta(6)-p-cymene)Ru(lysozyme)Cl(2)], the first of a half-sandwich complex of a protein, shows selective ruthenation of Nepsilon of the imidazole ring of His15. |
==About this Structure== | ==About this Structure== | ||
| - | 1T3P is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] with CL, NA, ACT and RU7 as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] Full crystallographic information is available from [http:// | + | 1T3P is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] with <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=ACT:'>ACT</scene> and <scene name='pdbligand=RU7:'>RU7</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T3P OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Fishburne, K.]] | [[Category: Fishburne, K.]] | ||
[[Category: Habtemariam, A.]] | [[Category: Habtemariam, A.]] | ||
| - | [[Category: Hunter, T | + | [[Category: Hunter, T M.]] |
| - | [[Category: McNae, I | + | [[Category: McNae, I W.]] |
[[Category: Melchart, M.]] | [[Category: Melchart, M.]] | ||
| - | [[Category: Sadler, P | + | [[Category: Sadler, P J.]] |
| - | [[Category: Walkinshaw, M | + | [[Category: Walkinshaw, M D.]] |
[[Category: Wang, F.]] | [[Category: Wang, F.]] | ||
[[Category: ACT]] | [[Category: ACT]] | ||
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[[Category: tetragonal lysozyme]] | [[Category: tetragonal lysozyme]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:09:32 2008'' |
Revision as of 13:09, 21 February 2008
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Half-sandwich arene ruthenium(II)-enzyme complex
Overview
The 1.6 [Angstrom] X-ray crystal structure of [(eta(6)-p-cymene)Ru(lysozyme)Cl(2)], the first of a half-sandwich complex of a protein, shows selective ruthenation of Nepsilon of the imidazole ring of His15.
About this Structure
1T3P is a Single protein structure of sequence from Gallus gallus with , , and as ligands. Active as Lysozyme, with EC number 3.2.1.17 Full crystallographic information is available from OCA.
Reference
Half-sandwich arene ruthenium(II)-enzyme complex., McNae IW, Fishburne K, Habtemariam A, Hunter TM, Melchart M, Wang F, Walkinshaw MD, Sadler PJ, Chem Commun (Camb). 2004 Aug 21;(16):1786-7. Epub 2004 Jul 27. PMID:15306883
Page seeded by OCA on Thu Feb 21 15:09:32 2008
Categories: Gallus gallus | Lysozyme | Single protein | Fishburne, K. | Habtemariam, A. | Hunter, T M. | McNae, I W. | Melchart, M. | Sadler, P J. | Walkinshaw, M D. | Wang, F. | ACT | CL | NA | RU7 | Ruthenium | Tetragonal lysozyme
