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1t6s
From Proteopedia
(New page: 200px<br /><applet load="1t6s" size="450" color="white" frame="true" align="right" spinBox="true" caption="1t6s, resolution 1.95Å" /> '''Crystal structure of...) |
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| - | [[Image:1t6s.jpg|left|200px]]<br /><applet load="1t6s" size=" | + | [[Image:1t6s.jpg|left|200px]]<br /><applet load="1t6s" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="1t6s, resolution 1.95Å" /> | caption="1t6s, resolution 1.95Å" /> | ||
'''Crystal structure of a conserved hypothetical protein from Chlorobium tepidum'''<br /> | '''Crystal structure of a conserved hypothetical protein from Chlorobium tepidum'''<br /> | ||
==Overview== | ==Overview== | ||
| - | Structural maintenance of chromosome (SMC) proteins are essential in | + | Structural maintenance of chromosome (SMC) proteins are essential in chromosome condensation and interact with non-SMC proteins in eukaryotes and with segregation and condensation proteins (ScpA and ScpB) in prokaryotes. The highly conserved gene in Chlorobium tepidum gi 21646405 encodes ScpB (ScpB_ChTe). The high resolution crystal structure of ScpB_ChTe shows that the monomeric structure consists of two similarly shaped globular domains composed of three helices sided by beta-strands [a winged helix-turn-helix (HTH)], a motif observed in the C-terminal domain of Scc1, a functionally related eukaryotic ScpA homolog, as well as in many DNA binding proteins. |
==About this Structure== | ==About this Structure== | ||
| - | 1T6S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Chlorobium_tepidum_tls Chlorobium tepidum tls] with NO3 as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http:// | + | 1T6S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Chlorobium_tepidum_tls Chlorobium tepidum tls] with <scene name='pdbligand=NO3:'>NO3</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T6S OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Chlorobium tepidum tls]] | [[Category: Chlorobium tepidum tls]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: BSGC, Berkeley | + | [[Category: BSGC, Berkeley Structural Genomics Center.]] |
| - | [[Category: Kim, J | + | [[Category: Kim, J S.]] |
[[Category: Kim, R.]] | [[Category: Kim, R.]] | ||
| - | [[Category: Kim, S | + | [[Category: Kim, S H.]] |
| - | [[Category: Shin, D | + | [[Category: Shin, D H.]] |
[[Category: NO3]] | [[Category: NO3]] | ||
[[Category: a winged helix-turn-helix]] | [[Category: a winged helix-turn-helix]] | ||
| Line 26: | Line 26: | ||
[[Category: structural genomics]] | [[Category: structural genomics]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:10:28 2008'' |
Revision as of 13:10, 21 February 2008
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Crystal structure of a conserved hypothetical protein from Chlorobium tepidum
Overview
Structural maintenance of chromosome (SMC) proteins are essential in chromosome condensation and interact with non-SMC proteins in eukaryotes and with segregation and condensation proteins (ScpA and ScpB) in prokaryotes. The highly conserved gene in Chlorobium tepidum gi 21646405 encodes ScpB (ScpB_ChTe). The high resolution crystal structure of ScpB_ChTe shows that the monomeric structure consists of two similarly shaped globular domains composed of three helices sided by beta-strands [a winged helix-turn-helix (HTH)], a motif observed in the C-terminal domain of Scc1, a functionally related eukaryotic ScpA homolog, as well as in many DNA binding proteins.
About this Structure
1T6S is a Single protein structure of sequence from Chlorobium tepidum tls with as ligand. Full crystallographic information is available from OCA.
Reference
Crystal structure of ScpB from Chlorobium tepidum, a protein involved in chromosome partitioning., Kim JS, Shin DH, Pufan R, Huang C, Yokota H, Kim R, Kim SH, Proteins. 2006 Feb 1;62(2):322-8. PMID:16294331
Page seeded by OCA on Thu Feb 21 15:10:28 2008
Categories: Chlorobium tepidum tls | Single protein | BSGC, Berkeley Structural Genomics Center. | Kim, J S. | Kim, R. | Kim, S H. | Shin, D H. | NO3 | A winged helix-turn-helix | Berkeley structural genomics center | Bsgc structure funded by nih | Protein structure initiative | Psi | Structural genomics
