1q7g

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Revision as of 09:52, 2 January 2013

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Template:STRUCTURE 1q7g

Homoserine Dehydrogenase in complex with suicide inhibitor complex NAD-5-hydroxy-4-Oxonorvaline

Template:ABSTRACT PUBMED 14583265

About this Structure

1q7g is a 2 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

• Jacques SL, Mirza IA, Ejim L, Koteva K, Hughes DW, Green K, Kinach R, Honek JF, Lai HK, Berghuis AM, Wright GD. Enzyme-assisted suicide: molecular basis for the antifungal activity of 5-hydroxy-4-oxonorvaline by potent inhibition of homoserine dehydrogenase. Chem Biol. 2003 Oct;10(10):989-95. PMID:14583265