This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1ra0
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
[[Image:1ra0.png|left|200px]] | [[Image:1ra0.png|left|200px]] | ||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_1ra0", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_1ra0| PDB=1ra0 | SCENE= }} | {{STRUCTURE_1ra0| PDB=1ra0 | SCENE= }} | ||
===Bacterial cytosine deaminase D314G mutant bound to 5-fluoro-4-(S)-hydroxy-3,4-dihydropyrimidine.=== | ===Bacterial cytosine deaminase D314G mutant bound to 5-fluoro-4-(S)-hydroxy-3,4-dihydropyrimidine.=== | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, {{ABSTRACT_PUBMED_15381761}}, adds the Publication Abstract to the page | ||
| - | (as it appears on PubMed at http://www.pubmed.gov), where 15381761 is the PubMed ID number. | ||
| - | --> | ||
{{ABSTRACT_PUBMED_15381761}} | {{ABSTRACT_PUBMED_15381761}} | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1ra0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RA0 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015381761</ref><references group="xtra"/> |
[[Category: Cytosine deaminase]] | [[Category: Cytosine deaminase]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| Line 35: | Line 23: | ||
[[Category: D314g mutant]] | [[Category: D314g mutant]] | ||
[[Category: Hexamer]] | [[Category: Hexamer]] | ||
| - | + | [[Category: Hydrolase]] | |
| - | + | ||
Revision as of 09:59, 4 January 2013
Bacterial cytosine deaminase D314G mutant bound to 5-fluoro-4-(S)-hydroxy-3,4-dihydropyrimidine.
Template:ABSTRACT PUBMED 15381761
About this Structure
1ra0 is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
- Mahan SD, Ireton GC, Knoeber C, Stoddard BL, Black ME. Random mutagenesis and selection of Escherichia coli cytosine deaminase for cancer gene therapy. Protein Eng Des Sel. 2004 Aug;17(8):625-33. Epub 2004 Sep 20. PMID:15381761 doi:10.1093/protein/gzh074
