1sqt

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{{Seed}}
 
[[Image:1sqt.png|left|200px]]
[[Image:1sqt.png|left|200px]]
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{{STRUCTURE_1sqt| PDB=1sqt | SCENE= }}
{{STRUCTURE_1sqt| PDB=1sqt | SCENE= }}
===Substituted 2-Naphthamidine Inhibitors of Urokinase===
===Substituted 2-Naphthamidine Inhibitors of Urokinase===
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{{ABSTRACT_PUBMED_15149645}}
{{ABSTRACT_PUBMED_15149645}}
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==Disease==
 
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Known disease associated with this structure: Alzheimer disease, late-onset, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191840 191840]]
 
==About this Structure==
==About this Structure==
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1SQT is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SQT OCA].
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[[1sqt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SQT OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:15149645</ref><references group="xtra"/>
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<ref group="xtra">PMID:015149645</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: U-plasminogen activator]]
[[Category: U-plasminogen activator]]
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[[Category: Plasminogen activation]]
[[Category: Plasminogen activation]]
[[Category: Serine protease]]
[[Category: Serine protease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 22:02:01 2009''
 

Revision as of 10:02, 4 January 2013

Template:STRUCTURE 1sqt

Substituted 2-Naphthamidine Inhibitors of Urokinase

Template:ABSTRACT PUBMED 15149645

About this Structure

1sqt is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wendt MD, Geyer A, McClellan WJ, Rockway TW, Weitzberg M, Zhao X, Mantei R, Stewart K, Nienaber V, Klinghofer V, Giranda VL. Interaction with the S1 beta-pocket of urokinase: 8-heterocycle substituted and 6,8-disubstituted 2-naphthamidine urokinase inhibitors. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3063-8. PMID:15149645 doi:10.1016/j.bmcl.2004.04.030

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