1sqt
From Proteopedia
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[[Image:1sqt.png|left|200px]] | [[Image:1sqt.png|left|200px]] | ||
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{{STRUCTURE_1sqt| PDB=1sqt | SCENE= }} | {{STRUCTURE_1sqt| PDB=1sqt | SCENE= }} | ||
===Substituted 2-Naphthamidine Inhibitors of Urokinase=== | ===Substituted 2-Naphthamidine Inhibitors of Urokinase=== | ||
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{{ABSTRACT_PUBMED_15149645}} | {{ABSTRACT_PUBMED_15149645}} | ||
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- | ==Disease== | ||
- | Known disease associated with this structure: Alzheimer disease, late-onset, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191840 191840]] | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[1sqt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SQT OCA]. | |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:015149645</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: U-plasminogen activator]] | [[Category: U-plasminogen activator]] | ||
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[[Category: Plasminogen activation]] | [[Category: Plasminogen activation]] | ||
[[Category: Serine protease]] | [[Category: Serine protease]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 22:02:01 2009'' |
Revision as of 10:02, 4 January 2013
Substituted 2-Naphthamidine Inhibitors of Urokinase
Template:ABSTRACT PUBMED 15149645
About this Structure
1sqt is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wendt MD, Geyer A, McClellan WJ, Rockway TW, Weitzberg M, Zhao X, Mantei R, Stewart K, Nienaber V, Klinghofer V, Giranda VL. Interaction with the S1 beta-pocket of urokinase: 8-heterocycle substituted and 6,8-disubstituted 2-naphthamidine urokinase inhibitors. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3063-8. PMID:15149645 doi:10.1016/j.bmcl.2004.04.030
Categories: Homo sapiens | U-plasminogen activator | Geyer, A. | Giranda, V L. | Klinghofer, V. | Mantei, R. | McClellan, W J. | Nienaber, V. | Rockway, T W. | Stewart, K. | Weitzberg, M. | Wendt, M D. | Zhang, X. | Egf-like domain | Glycoprotein | Hydrolase | Kringle | Plasminogen activation | Serine protease