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1rqq
From Proteopedia
(Difference between revisions)
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[[Image:1rqq.png|left|200px]] | [[Image:1rqq.png|left|200px]] | ||
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{{STRUCTURE_1rqq| PDB=1rqq | SCENE= }} | {{STRUCTURE_1rqq| PDB=1rqq | SCENE= }} | ||
===Crystal Structure of the Insulin Receptor Kinase in Complex with the SH2 Domain of APS=== | ===Crystal Structure of the Insulin Receptor Kinase in Complex with the SH2 Domain of APS=== | ||
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{{ABSTRACT_PUBMED_14690593}} | {{ABSTRACT_PUBMED_14690593}} | ||
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| - | ==Disease== | ||
| - | Known disease associated with this structure: Diabetes mellitus, insulin-resistant, with acanthosis nigricans OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Hyperinsulinemic hypoglycemia, familial, 5 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Leprechaunism OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]], Rabson-Mendenhall syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147670 147670]] | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[1rqq]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RQQ OCA]. | |
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| + | ==See Also== | ||
| + | *[[Insulin receptor|Insulin receptor]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:014690593</ref><references group="xtra"/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
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[[Category: Protein tyrosine kinase]] | [[Category: Protein tyrosine kinase]] | ||
[[Category: Sh2 domain]] | [[Category: Sh2 domain]] | ||
| - | + | [[Category: Transferase-signaling protein complex]] | |
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Revision as of 10:14, 4 January 2013
Contents |
Crystal Structure of the Insulin Receptor Kinase in Complex with the SH2 Domain of APS
Template:ABSTRACT PUBMED 14690593
About this Structure
1rqq is a 6 chain structure with sequence from Homo sapiens and Rattus norvegicus. Full crystallographic information is available from OCA.
See Also
Reference
- Hu J, Liu J, Ghirlando R, Saltiel AR, Hubbard SR. Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor. Mol Cell. 2003 Dec;12(6):1379-89. PMID:14690593
