1r0p

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[[Image:1r0p.png|left|200px]]
[[Image:1r0p.png|left|200px]]
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{{STRUCTURE_1r0p| PDB=1r0p | SCENE= }}
{{STRUCTURE_1r0p| PDB=1r0p | SCENE= }}
===Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met in complex with the microbial alkaloid K-252a===
===Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met in complex with the microbial alkaloid K-252a===
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{{ABSTRACT_PUBMED_14559966}}
{{ABSTRACT_PUBMED_14559966}}
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==Disease==
 
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Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Renal cell carcinoma, papillary, familial and sporadic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Autism, suseptibility to, 9 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]]
 
==About this Structure==
==About this Structure==
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1R0P is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R0P OCA].
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[[1r0p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R0P OCA].
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==See Also==
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*[[Hepatocyte growth factor receptor|Hepatocyte growth factor receptor]]
==Reference==
==Reference==
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<ref group="xtra">PMID:14559966</ref><references group="xtra"/>
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<ref group="xtra">PMID:014559966</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Transferase]]
[[Category: Transferase]]
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[[Category: Shc]]
[[Category: Shc]]
[[Category: Signal transduction]]
[[Category: Signal transduction]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:33:29 2009''
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Revision as of 10:24, 4 January 2013

Image:1r0p.png


PDB ID 1r0p

Drag the structure with the mouse to rotate
1r0p, resolution 1.80Å ()
Ligands:
Gene: MET (Homo sapiens)
Activity: Transferase, with EC number and 2.7.10.2 2.7.10.1 and 2.7.10.2
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Contents

Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met in complex with the microbial alkaloid K-252a

Template:ABSTRACT PUBMED 14559966

About this Structure

1r0p is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Schiering N, Knapp S, Marconi M, Flocco MM, Cui J, Perego R, Rusconi L, Cristiani C. Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-Met and its complex with the microbial alkaloid K-252a. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12654-9. Epub 2003 Oct 14. PMID:14559966 doi:10.1073/pnas.1734128100

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