1s64

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Image:1s64.png

Template:STRUCTURE 1s64

Rat protein geranylgeranyltransferase type-I complexed with L-778,123 and a sulfate anion

Template:ABSTRACT PUBMED 15248757

About this Structure

1s64 is a 12 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Reid TS, Long SB, Beese LS. Crystallographic analysis reveals that anticancer clinical candidate L-778,123 inhibits protein farnesyltransferase and geranylgeranyltransferase-I by different binding modes. Biochemistry. 2004 Jul 20;43(28):9000-8. PMID:15248757 doi:10.1021/bi049280b

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OCA

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