1rqc

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Revision as of 10:35, 4 January 2013

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Template:STRUCTURE 1rqc

Crystals of peptide deformylase from Plasmodium falciparum with ten subunits per asymmetric unit reveal critical characteristics of the active site for drug design

Template:ABSTRACT PUBMED 15010544

About this Structure

1rqc is a 10 chain structure with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.

Reference

• Robien MA, Nguyen KT, Kumar A, Hirsh I, Turley S, Pei D, Hol WG. An improved crystal form of Plasmodium falciparum peptide deformylase. Protein Sci. 2004 Apr;13(4):1155-63. Epub 2004 Mar 9. PMID:15010544 doi:http://dx.doi.org/10.1110/ps.03456404
• Joshi AA, Viswanathan CL. Docking studies and development of novel 5-heteroarylamino-2,4-diamino-8-chloropyrimido-[4,5-b]quinolines as potential antimalarials. Bioorg Med Chem Lett. 2006 May 15;16(10):2613-7. Epub 2006 Mar 3. PMID:16516468 doi:10.1016/j.bmcl.2006.02.038