1siv
From Proteopedia
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===THREE-DIMENSIONAL STRUCTURE OF A SIV PROTEASE(SLASH)INHIBITOR COMPLEX. IMPLICATIONS FOR THE DESIGN OF HIV-1 AND HIV-2 PROTEASE INHIBITORS=== | ===THREE-DIMENSIONAL STRUCTURE OF A SIV PROTEASE(SLASH)INHIBITOR COMPLEX. IMPLICATIONS FOR THE DESIGN OF HIV-1 AND HIV-2 PROTEASE INHIBITORS=== | ||
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{{ABSTRACT_PUBMED_8241159}} | {{ABSTRACT_PUBMED_8241159}} | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[1siv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Simian_immunodeficiency_virus Simian immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SIV OCA]. | |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:008241159</ref><ref group="xtra">PMID:011152609</ref><references group="xtra"/> |
[[Category: Simian immunodeficiency virus]] | [[Category: Simian immunodeficiency virus]] | ||
[[Category: Abdel-Meguid, S.]] | [[Category: Abdel-Meguid, S.]] | ||
[[Category: Zhao, B.]] | [[Category: Zhao, B.]] | ||
- | + | [[Category: Acid proteinase]] | |
- | + | [[Category: Hydrolase-hydrolase inhibitor complex]] |
Revision as of 10:52, 4 January 2013
THREE-DIMENSIONAL STRUCTURE OF A SIV PROTEASE(SLASH)INHIBITOR COMPLEX. IMPLICATIONS FOR THE DESIGN OF HIV-1 AND HIV-2 PROTEASE INHIBITORS
Template:ABSTRACT PUBMED 8241159
About this Structure
1siv is a 2 chain structure with sequence from Simian immunodeficiency virus. Full crystallographic information is available from OCA.
Reference
- Zhao B, Winborne E, Minnich MD, Culp JS, Debouck C, Abdel-Meguid SS. Three-dimensional structure of a simian immunodeficiency virus protease/inhibitor complex. Implications for the design of human immunodeficiency virus type 1 and 2 protease inhibitors. Biochemistry. 1993 Dec 7;32(48):13054-60. PMID:8241159
- Ishima R, Louis JM, Torchia DA. Characterization of two hydrophobic methyl clusters in HIV-1 protease by NMR spin relaxation in solution. J Mol Biol. 2001 Jan 19;305(3):515-21. PMID:11152609 doi:10.1006/jmbi.2000.4321