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'''The complex of wild type B-RAF and BAY439006'''
'''The complex of wild type B-RAF and BAY439006'''
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[[Image:1uwh bio r 500.jpg|300px|thumb| The complex of wild type B-RAF and BAY439006 ]]
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[[Image:1uwh bio r 500.jpg|300px|thumb| The complex of wild type B-RAF and BAY439006]]
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== References ==
== References ==
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1. Wan, P.T.C., Garnett, M.J., Roe, S.M., Lee, S., Niculescu-Duvaz, D., Good, V.M., Jones, C.M., Marshall, C.J., Springer, C.J., Barford, D., Marais, R. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell. 2004 Mar 19;116(6):855-67. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15035987 15035987]
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1. Wan, P.T.C., Garnett, M.J., Roe, S.M., Lee, S., Niculescu-Duvaz, D., Good, V.M., Jones, C.M., Marshall, C.J., Springer, C.J., Barford, D., Marais, R. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell. 2004 Mar 19;116(6):855-67. <ref>PMID: 15035987</ref>
== Protreopedia Page Contributors and Editors ==
== Protreopedia Page Contributors and Editors ==
Kostika Sofroni and Gilles Dupouy
Kostika Sofroni and Gilles Dupouy

Revision as of 11:39, 4 January 2013

Template:Sandbox ESBS 2012


The complex of wild type B-RAF and BAY439006

The complex of wild type B-RAF and BAY439006
The complex of wild type B-RAF and BAY439006


Contents

Introduction

3D View of the complex

Drag the structure with the mouse to rotate

Structure

Regulation

Other Inhibitors

External Ressources

PDB file for 1UWH

References

1. Wan, P.T.C., Garnett, M.J., Roe, S.M., Lee, S., Niculescu-Duvaz, D., Good, V.M., Jones, C.M., Marshall, C.J., Springer, C.J., Barford, D., Marais, R. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell. 2004 Mar 19;116(6):855-67. [1]

Protreopedia Page Contributors and Editors

Kostika Sofroni and Gilles Dupouy

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