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1u5b

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[[Image:1u5b.png|left|200px]]
[[Image:1u5b.png|left|200px]]
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{{STRUCTURE_1u5b| PDB=1u5b | SCENE= }}
{{STRUCTURE_1u5b| PDB=1u5b | SCENE= }}
===Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase===
===Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase===
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{{ABSTRACT_PUBMED_15576032}}
{{ABSTRACT_PUBMED_15576032}}
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==Disease==
 
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Known disease associated with this structure: Maple syrup urine disease, type Ia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=608348 608348]], Maple syrup urine disease, type Ib OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=248611 248611]]
 
==About this Structure==
==About this Structure==
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1U5B is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U5B OCA].
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[[1u5b]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U5B OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:15576032</ref><references group="xtra"/>
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<ref group="xtra">PMID:015576032</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Chuang, D T.]]
[[Category: Chuang, D T.]]
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[[Category: Branched-chain]]
[[Category: Branched-chain]]
[[Category: Flavoprotein]]
[[Category: Flavoprotein]]
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[[Category: Ketoacid dehydrogenase]]
[[Category: Multi-enzyme complex]]
[[Category: Multi-enzyme complex]]
[[Category: Oxidative decarboxylation maple syrup urine disease]]
[[Category: Oxidative decarboxylation maple syrup urine disease]]
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[[Category: Oxidoreductase,ketoacid dehydrogenase]]
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[[Category: Oxidoreductase]]
[[Category: Phosphorylation]]
[[Category: Phosphorylation]]
[[Category: Thiamin diphosphate]]
[[Category: Thiamin diphosphate]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:03:25 2009''
 

Revision as of 11:42, 5 January 2013

Template:STRUCTURE 1u5b

Crystal structure of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase

Template:ABSTRACT PUBMED 15576032

About this Structure

1u5b is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Wynn RM, Kato M, Machius M, Chuang JL, Li J, Tomchick DR, Chuang DT. Molecular mechanism for regulation of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase complex by phosphorylation. Structure. 2004 Dec;12(12):2185-96. PMID:15576032 doi:10.1016/j.str.2004.09.013

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