1t2v

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{{Seed}}
 
[[Image:1t2v.png|left|200px]]
[[Image:1t2v.png|left|200px]]
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{{STRUCTURE_1t2v| PDB=1t2v | SCENE= }}
{{STRUCTURE_1t2v| PDB=1t2v | SCENE= }}
===Structural basis of phospho-peptide recognition by the BRCT domain of BRCA1, structure with phosphopeptide===
===Structural basis of phospho-peptide recognition by the BRCT domain of BRCA1, structure with phosphopeptide===
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{{ABSTRACT_PUBMED_15133503}}
{{ABSTRACT_PUBMED_15133503}}
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==Disease==
 
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Known disease associated with this structure: Breast cancer-1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Breast-ovarian cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Ovarian cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]], Papillary serous carcinoma of the peritoneum OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=113705 113705]]
 
==About this Structure==
==About this Structure==
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1T2V is a 10 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T2V OCA].
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[[1t2v]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T2V OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:15133503</ref><references group="xtra"/>
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<ref group="xtra">PMID:015133503</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Glover, J N.M.]]
[[Category: Glover, J N.M.]]
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[[Category: Lee, M S.]]
[[Category: Lee, M S.]]
[[Category: Williams, R S.]]
[[Category: Williams, R S.]]
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[[Category: Antitumor protein]]
[[Category: Brca1]]
[[Category: Brca1]]
[[Category: Brct]]
[[Category: Brct]]
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[[Category: Missense mutation]]
[[Category: Missense mutation]]
[[Category: Phosphopeptide]]
[[Category: Phosphopeptide]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:57:16 2009''
 

Revision as of 11:43, 5 January 2013

Template:STRUCTURE 1t2v

Structural basis of phospho-peptide recognition by the BRCT domain of BRCA1, structure with phosphopeptide

Template:ABSTRACT PUBMED 15133503

About this Structure

1t2v is a 10 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Williams RS, Lee MS, Hau DD, Glover JN. Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1. Nat Struct Mol Biol. 2004 Jun;11(6):519-25. Epub 2004 May 9. PMID:15133503 doi:http://dx.doi.org/10.1038/nsmb776

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